From the Research
Pityriasis rosea is likely viral in origin, with human herpesvirus 6 (HHV-6) and human herpesvirus 7 (HHV-7) being the most strongly implicated potential causative agents, as supported by the most recent and highest quality study 1. The condition typically presents with a herald patch, followed by a secondary eruption of oval, erythematous, scaly lesions on the trunk and proximal extremities, often in a Christmas tree-like distribution.
- The viral theory is supported by several observations, including:
- Community outbreaks
- Rare recurrence, suggesting immunity development
- Self-limited course, typical of viral infections
- Prodromal symptoms, similar to those seen in viral illnesses
- Management focuses on symptom relief, with:
- Antihistamines for itching
- Topical steroids for inflammation
- Moisturizers for dry skin
- In severe cases, short courses of oral steroids or UVB phototherapy may be considered, although antiviral medications like acyclovir are not standard treatment due to limited evidence of benefit 1. The characteristic presentation of pityriasis rosea reflects a viral-mediated immune response pattern, with HHV-6 and HHV-7 being the most likely causative agents, as suggested by the most recent study 1.