What is the diagnosis for a thoracic spine X-ray showing maintained bony alignment, no focal bony lesions, and trivial multilevel endplate anterior osteophytic (bone spurs) degenerative lipping?

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Last updated: May 18, 2025 • View editorial policy

Differential Diagnosis for Thoracic Spine X-Ray Findings

  • Single most likely diagnosis + Degenerative disc disease: This is the most likely diagnosis given the presence of trivial multilevel endplate anterior osteophytic degenerative lipping, which is a common finding in degenerative disc disease.
  • Other Likely diagnoses + Spondylosis: This condition is characterized by degenerative changes in the spine, including osteophyte formation, and is a likely diagnosis given the X-ray findings. + Musculoskeletal strain: The presence of degenerative changes and maintained bony alignment suggests that musculoskeletal strain could be a contributing factor to the patient's symptoms.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.) + Spinal infection (e.g., osteomyelitis, discitis): Although the X-ray findings do not suggest an infection, it is essential to consider this possibility, as spinal infections can be devastating if left untreated. + Spinal tumor: Although the X-ray findings do not indicate a focal bony lesion, it is crucial to rule out a spinal tumor, as it can have severe consequences if missed. + Fracture: Although the bony alignment is maintained, it is essential to consider the possibility of a fracture, particularly if the patient has a history of trauma.
  • Rare diagnoses + Ankylosing spondylitis: This is a rare inflammatory condition that can cause degenerative changes in the spine, although it is less likely given the absence of significant bony fusion or sacroiliitis on the X-ray. + Diffuse idiopathic skeletal hyperostosis (DISH): This is a rare condition characterized by excessive bone growth, which could potentially cause osteophyte formation, although it is less likely given the trivial nature of the findings.

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