Which cranial nerves should be assessed after thyroidectomy (thyroid removal)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 20, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

After a thyroidectomy, it's crucial to check cranial nerves X (vagus) and XII (hypoglossal) to minimize morbidity, mortality, and improve quality of life. Here's what you need to know:

  • Cranial Nerve X (Vagus):
    • Test: Ask the patient to say "Ah" and observe for symmetrical palatal elevation, as recommended by the clinical practice guideline: improving voice outcomes after thyroid surgery 1.
    • Reason: The recurrent laryngeal nerve, a branch of the vagus, can be injured during thyroid surgery, leading to vocal cord paralysis, which can significantly impact a patient's quality of life 1.
  • Cranial Nerve XII (Hypoglossal):
    • Test: Ask the patient to stick out their tongue and move it side to side.
    • Reason: While less common, the hypoglossal nerve can be affected due to its proximity to the surgical site, and its injury can lead to difficulties in swallowing and speaking, ultimately affecting the patient's morbidity and mortality 1. Additionally, assess for:
  • Voice changes (hoarseness, breathiness)
  • Swallowing difficulties
  • Neck swelling or hematoma Perform these checks immediately post-op and during follow-up visits, as early detection of nerve injury allows for prompt intervention, potentially improving outcomes, and reducing the risk of long-term complications, as highlighted in the study by Chandrasekhar et al 1. If any abnormalities are found, consult with an otolaryngologist for further evaluation and management, to ensure the best possible outcome for the patient in terms of morbidity, mortality, and quality of life.

From the Research

Cranial Nerves to be Assessed after Thyroidectomy

The cranial nerves that should be assessed after thyroidectomy are:

  • Recurrent laryngeal nerve (RLN) 2, 3, 4, 5
  • External branch of the superior laryngeal nerve (EBSLN) 2, 6, 5

Reasons for Assessment

These nerves are at risk of injury during thyroidectomy due to their close anatomical relationship with the thyroid gland and surrounding structures. Injury to these nerves can result in vocal cord paralysis, hoarseness, and other complications.

Key Points

  • The RLN provides motor innervation to the intrinsic laryngeal muscles and sensory innervation to the larynx 2, 3, 4, 5
  • The EBSLN provides motor innervation to the cricothyroid muscle, which is the tensor muscle of the vocal cord 2, 6, 5
  • Intraoperative nerve monitoring (IONM) can be used to assess the functional integrity of the RLN and EBSLN 2, 5
  • Visual control and gentle dissection of the RLN and EBSLN are imperative to prevent injury 2, 3, 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

The recurrent laryngeal nerve related to thyroid surgery.

American journal of surgery, 1999

Research

Post-thyroidectomy superior laryngeal nerve injury.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2001

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.