What causes buttock pain after a thigh biopsy?

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Last updated: May 18, 2025View editorial policy

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Differential Diagnosis for Butt Ache after Thigh Biopsy

  • Single most likely diagnosis
    • Hematoma: This is the most likely diagnosis as a thigh biopsy can cause bleeding into the surrounding tissue, leading to a hematoma, which can cause pain and discomfort in the buttock area.
  • Other Likely diagnoses
    • Infection: Bacterial infection is a possible complication of a biopsy, and it can cause pain, redness, and swelling in the affected area.
    • Nerve damage: The biopsy procedure can cause damage to the surrounding nerves, leading to pain, numbness, or tingling in the buttock area.
    • Seroma: A seroma is a collection of fluid that can occur at the site of the biopsy, causing pain and discomfort.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Necrotizing fasciitis: This is a rare but life-threatening infection that can occur after a biopsy, causing severe pain, swelling, and necrosis of the tissue.
    • Deep vein thrombosis (DVT): A DVT can occur after a biopsy, especially if the patient is immobile, and it can cause pain and swelling in the leg.
    • Compartment syndrome: This is a condition where the pressure in the muscle compartment increases, causing pain, numbness, and tingling, and it can be a complication of a biopsy.
  • Rare diagnoses
    • Pseudotumor: A pseudotumor is a rare complication of a biopsy, where a mass of tissue forms at the site of the biopsy, causing pain and discomfort.
    • Foreign body reaction: A foreign body reaction can occur if a foreign object, such as a suture or a fragment of the biopsy needle, is left in the tissue, causing pain and inflammation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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