What is the differential diagnosis (Ddx) for a burning sensation while urinating, also known as dysuria?

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Differential Diagnosis for Burning Sensation while Urinating

Single Most Likely Diagnosis

  • Urinary Tract Infection (UTI): This is the most common cause of dysuria (burning sensation while urinating), especially in women. Bacteria such as E. coli are often the culprit, leading to inflammation and irritation of the urinary tract.

Other Likely Diagnoses

  • Sexually Transmitted Infections (STIs): Infections like chlamydia, gonorrhea, and herpes can cause dysuria due to the inflammation and irritation of the genital and urinary tract areas.
  • Urethritis: Inflammation of the urethra, often caused by infection or irritation, can lead to a burning sensation during urination.
  • Prostatitis: Inflammation of the prostate gland, which can be caused by infection or other factors, may cause dysuria in men.

Do Not Miss Diagnoses

  • Kidney Stones: Although less common, kidney stones can cause severe pain and dysuria. Missing this diagnosis could lead to complications like kidney damage if not promptly treated.
  • Interstitial Cystitis: A chronic condition causing bladder pressure, bladder pain, and sometimes dysuria. It's crucial not to miss this diagnosis to provide appropriate management and prevent long-term bladder damage.
  • Tuberculosis of the Urinary Tract: A rare but serious condition that can cause dysuria among other symptoms. It's essential to consider this in the differential diagnosis, especially in high-risk populations or areas with high TB prevalence.

Rare Diagnoses

  • Bladder Cancer: Although rare, bladder cancer can cause dysuria. It's more common in older adults and those with a history of smoking.
  • Sjögren's Syndrome: An autoimmune disorder that can cause dryness in various parts of the body, including the bladder, leading to dysuria.
  • Chemical Cystitis: Irritation of the bladder due to certain chemicals, such as those found in some foods or products, can cause a burning sensation during urination.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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