What is the most common bacterial infection from seafood on the East Coast, specifically Campylobacter (Campylobacter infection)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 19, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Vibrio species, particularly Vibrio parahaemolyticus and Vibrio vulnificus, are the most common bacterial pathogens associated with seafood consumption on the East Coast of the United States, not Campylobacter. These bacteria naturally occur in coastal waters and can concentrate in filter-feeding shellfish like oysters, clams, and mussels, especially during warmer months 1. Symptoms of Vibrio infection typically include diarrhea, abdominal cramps, nausea, vomiting, and fever, usually appearing within 24 hours of consumption.

Key Considerations

  • For mild to moderate cases, treatment involves oral rehydration and possibly antibiotics like doxycycline (100mg twice daily for 3 days) or ciprofloxacin (500mg twice daily for 3 days) 1.
  • Severe infections, particularly with Vibrio vulnificus, may require hospitalization with intravenous antibiotics.
  • To prevent these infections, consumers should cook seafood thoroughly, avoid raw shellfish (especially if immunocompromised), and practice proper food handling to prevent cross-contamination.

Prevention and Treatment

Some key points to consider in the prevention and treatment of Vibrio infections include:

  • Cooking seafood thoroughly to an internal temperature of at least 145°F (63°C) to kill bacteria.
  • Avoiding raw or undercooked shellfish, especially for people with weakened immune systems.
  • Practicing proper food handling and storage to prevent cross-contamination.
  • Washing hands frequently, especially after handling raw seafood.
  • Avoiding cross-contamination of utensils, cutting boards, and other kitchen surfaces.

From the Research

Bacterial Infections from Seafood

  • The most common bacterial infection from seafood on the east coast is not explicitly stated as Campylobacter in the provided studies, but rather Vibrio vulnificus is highlighted as a significant cause of seafood-related infections 2, 3, 4, 5.
  • Vibrio vulnificus is a gram-negative bacterium that can cause severe, potentially fatal infections, with case-fatality rates exceeding 50% for primary septicemia 2, 3, 4, 5.

Risk Factors and Transmission

  • Risk factors for Vibrio vulnificus infection include chronic liver disease, alcoholism, hematological disorders, and immunosuppression 3, 4, 5.
  • Transmission occurs primarily through the consumption of contaminated seafood, exposure of open wounds to infected water, or, in rare cases, insect bites 5.

Clinical Manifestations and Treatment

  • Clinical manifestations of Vibrio vulnificus infection range from localized gastrointestinal symptoms to life-threatening systemic infections such as septicemia 3, 4, 5.
  • Treatment typically involves the use of doxycycline in combination with third-generation cephalosporins, although the emergence of multidrug-resistant strains is an escalating concern 4, 5, 6.
  • Combination therapy, such as ceftriaxone-doxycycline or cefepime-doxycycline, has been shown to be effective in treating foodborne Vibrio vulnificus septicemia 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Vibrio vulnificus infection: diagnosis and treatment.

American family physician, 2007

Research

A comprehensive review of Vibrio vulnificus: an important cause of severe sepsis and skin and soft-tissue infection.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2011

Research

Vibrio vulnificus infection: a persistent threat to public health.

The Korean journal of internal medicine, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.