From the Research
Aloe vera has shown antiviral properties in laboratory studies, particularly against influenza virus, as evidenced by a 2019 study published in Phytomedicine, which found that aloin from Aloe vera leaves inhibited viral neuraminidase activity and boosted host immunity 1. However, it is essential to note that these findings have not been consistently translated into reliable clinical treatments for human viral infections. The current evidence base is limited by the lack of high-quality human clinical trials, and most studies have been conducted in vitro or in animal models. Some studies, such as the one published in The American journal of Chinese medicine in 2019, have identified specific compounds in aloe vera, like quercetin, catechin hydrate, and kaempferol, as potential antiviral agents against influenza A virus 2. Despite these promising results, the clinical effectiveness of aloe vera as an antiviral treatment remains uncertain, and its use should not replace established medical treatments for viral infections. In the context of real-life clinical medicine, prioritizing morbidity, mortality, and quality of life outcomes, the most recent and highest-quality study, published in 2021 in Phytotherapy research, suggests that aloe vera may have benefits in specific health outcomes, but the evidence is generally weak and limited by small sample sizes and poor methodological quality 3. Therefore, while aloe vera may be considered a complementary approach for soothing skin conditions, it should not be relied upon as a primary antiviral treatment, and patients should be aware of the variable quality and concentration of active compounds in commercial preparations. Key points to consider include:
- Aloe vera has shown antiviral properties in laboratory studies, particularly against influenza virus
- The current evidence base is limited by the lack of high-quality human clinical trials
- Specific compounds in aloe vera, like quercetin, catechin hydrate, and kaempferol, have been identified as potential antiviral agents
- The clinical effectiveness of aloe vera as an antiviral treatment remains uncertain
- Aloe vera should not replace established medical treatments for viral infections.