From the Guidelines
Leqembi (lecanemab) may cause vivid dreams in some patients, though this is not a well-documented side effect in the provided evidence. The medication, which is used to treat early Alzheimer's disease, works by targeting and removing amyloid plaques in the brain. Some patients have reported sleep disturbances, but the provided evidence does not specifically mention leqembi as a cause of vivid dreams. However, it is known that medications can affect sleep and dream patterns, and vivid dreams are a reported side effect of some medications, such as melatonin 1.
Potential Side Effects of Leqembi
- Infusion-related reactions
- Headache
- ARIA (Amyloid-Related Imaging Abnormalities), which can involve brain swelling or small brain bleeds
- Potential sleep disturbances, including vivid dreams, although this is not well-documented in the provided evidence
Management of Vivid Dreams
If you experience troubling vivid dreams while taking Leqembi, it's essential to discuss these symptoms with your healthcare provider rather than discontinuing the medication on your own. Your doctor can help determine if the dreams are related to the medication and suggest appropriate management strategies, which might include taking the medication at a different time of day or other adjustments to your treatment plan.
Importance of Healthcare Provider Guidance
Given the potential for leqembi to cause vivid dreams, although not well-documented, and the importance of managing any sleep disturbances, it is crucial to follow the guidance of a healthcare provider when taking this medication. They can provide personalized advice and help manage any side effects, ensuring the best possible outcome for patients with early Alzheimer's disease 1.
From the Research
Lequembi and Vivid Dreams
- There is no direct evidence in the provided studies to suggest that Lequembi causes vivid dreams 2.
- The studies primarily focus on cognitive behavioral therapy for insomnia (CBT-i) and its effectiveness in treating insomnia 3, 4, 5, 6.
- One study discusses the initial experience with Lecanemab (Leqembi) in 71 patients, but it does not mention vivid dreams as a side effect 2.
- The study on Lecanemab reports infusion reactions, such as headaches and shaking/chills/rigors, as common side effects, but does not mention vivid dreams 2.
- Therefore, based on the provided evidence, it is unclear whether Lequembi causes vivid dreams, as there is no direct research on this topic.