What is the diagnosis for a 42-year-old patient presenting with a 6-week history of a lump on the medial aspect of the left knee, associated with paresthesia (pins and needles sensation) and mild pain, following a twisting injury, with a bipartite patella noted on X-ray and pending Magnetic Resonance Imaging (MRI)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 19, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis

The patient presents with a lump on the medial aspect of the left knee, associated pins and needles sensation, and a history of twisting injury. The following differential diagnoses are considered:

  • Single most likely diagnosis
    • Meniscal cyst: The patient's symptoms of a lump on the medial aspect of the knee, associated with pins and needles sensation, and a history of twisting injury are consistent with a meniscal cyst. The presence of a bipartite patella on X-ray is a common finding, but the symptoms suggest a meniscal pathology.
  • Other Likely diagnoses
    • Medial meniscal tear: The patient's history of twisting injury and symptoms of pain and pins and needles sensation are consistent with a medial meniscal tear. The meniscal tear could be causing the lump and associated symptoms.
    • Prepatellar or pes anserine bursitis: The patient's symptoms of a lump on the medial aspect of the knee and pain could be consistent with prepatellar or pes anserine bursitis, although the associated pins and needles sensation is less typical.
    • Ganglion cyst: A ganglion cyst could present as a lump on the medial aspect of the knee, although the associated neurological symptoms are less common.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Osteosarcoma or other bone tumors: Although rare, bone tumors such as osteosarcoma could present with a lump on the knee and pain. It is essential to consider this diagnosis, especially if the MRI shows any suspicious findings.
    • Deep vein thrombosis (DVT): The patient's symptoms of pain and swelling could be consistent with a DVT, although the presence of a lump and pins and needles sensation is less typical. It is essential to consider this diagnosis, especially if the patient has any risk factors for DVT.
    • Nerve entrapment or compression: The patient's symptoms of pins and needles sensation and tingling could be consistent with nerve entrapment or compression, such as saphenous nerve entrapment.
  • Rare diagnoses
    • Synovial chondromatosis: This rare condition could present with a lump on the knee and pain, although it is less likely given the patient's symptoms and history.
    • Pigmented villonodular synovitis (PVNS): This rare condition could present with a lump on the knee and pain, although it is less likely given the patient's symptoms and history.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.