What is the cause of influenza-like illness with unexplained tachycardia (rapid heart rate)?

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Last updated: May 19, 2025View editorial policy

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Differential Diagnosis for Influenza-like Illness with Unexplained Tachycardia

  • Single most likely diagnosis
    • Influenza: The most common cause of influenza-like illness, which can present with tachycardia due to fever, dehydration, or the body's immune response.
  • Other Likely diagnoses
    • Respiratory Syncytial Virus (RSV) infection: Common in children and older adults, RSV can cause influenza-like symptoms and tachycardia.
    • Adenovirus infection: Adenoviruses can cause a range of respiratory symptoms, including influenza-like illness, and may lead to tachycardia.
    • Pneumonia: Bacterial or viral pneumonia can present with influenza-like symptoms and tachycardia due to infection and inflammation.
    • Bronchitis: Acute bronchitis, often caused by viral infections, can lead to influenza-like symptoms and tachycardia.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Sepsis: A life-threatening condition that can present with influenza-like symptoms and tachycardia, requiring prompt recognition and treatment.
    • Myocarditis: Inflammation of the heart muscle, which can be caused by viral infections, and may present with tachycardia and influenza-like symptoms.
    • Pulmonary embolism: A blockage of an artery in the lungs, which can cause tachycardia and may be preceded by influenza-like symptoms.
    • Meningitis: A severe infection of the meninges, which can present with influenza-like symptoms and tachycardia, especially in children and young adults.
  • Rare diagnoses
    • Hantavirus infection: A rare viral infection that can cause severe respiratory symptoms, including influenza-like illness and tachycardia.
    • Lymphocytic choriomeningitis (LCMV) infection: A rare viral infection that can cause influenza-like symptoms and tachycardia, often in immunocompromised individuals.
    • Tick-borne illnesses (e.g., Rocky Mountain spotted fever): Rare infections that can cause influenza-like symptoms and tachycardia, often with a history of tick exposure.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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