From the Guidelines
Decreasing stomach acid is not always the best approach to alleviate bloating, upset stomach, and frequent bowel movements, as it may worsen symptoms in certain conditions, such as diarrhea or irritable bowel syndrome (IBS) 1. When considering the management of functional dyspepsia (FD) or IBS, it's essential to identify the underlying cause of symptoms. According to the British Society of Gastroenterology guidelines, medications that reduce stomach acid, such as proton pump inhibitors (PPIs) or H2 blockers, may be beneficial for acid-related issues like heartburn or GERD, but not for diarrhea or frequent bowel movements 1.
Key Considerations
- The Low FODMAP Diet (LFD) has been shown to be an effective dietary treatment for patients with IBS, with studies demonstrating significant reductions in global symptoms, abdominal pain, and bloating 1.
- Simple remedies like avoiding trigger foods, eating smaller meals, staying hydrated, and managing stress can help alleviate bloating and upset stomach.
- If symptoms persist beyond two weeks or are severe, medical evaluation is necessary to rule out more serious conditions requiring different treatment approaches.
Treatment Approaches
- For patients with FD, the British Society of Gastroenterology guidelines recommend offering a stool test or breath test to look for a stomach infection called H. pylori, and treating it with antibiotics if positive 1.
- For patients with IBS, the LFD may be a useful treatment option, with a phased approach consisting of restriction, reintroduction, and personalization based on results from reintroduction 1.
- Psychological or behavioral therapies, such as neuromodulators, may also be beneficial for treating symptoms in FD and IBS, as they can help reduce abnormal sensitivity of the nerves in the upper gut 1.
From the FDA Drug Label
- Clinical Pharmacology 12. 1 Mechanism of Action Omeprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell Other Effects Systemic effects of omeprazole in the CNS, cardiovascular and respiratory systems have not been found to date No effect on gastric emptying of the solid and liquid components of a test meal was demonstrated after a single dose of omeprazole 90 mg.
The FDA drug label does not answer the question.