What is the recommended dose of Nasonex (mometasone furoate) in pediatric patients?

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Last updated: May 20, 2025View editorial policy

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From the Guidelines

Nasonex (mometasone furoate) nasal spray for children should be dosed at 1 spray (50 mcg) in each nostril once daily for children 2-11 years old and 2 sprays (100 mcg) in each nostril once daily for children 12 years and older, as recommended by the clinical practice guideline for allergic rhinitis 1. The dosing of Nasonex in children is based on age, with the goal of reducing inflammation in the nasal passages and relieving symptoms of allergic rhinitis such as sneezing, runny nose, and nasal congestion.

  • For children 2-11 years old, the recommended dose is one spray (50 mcg) in each nostril once daily.
  • For children 12 years and older, the dose is two sprays (100 mcg) in each nostril once daily. It is essential to use the medication at approximately the same time each day for best results and to continue it as prescribed even after symptoms improve to maintain control of nasal symptoms, as indicated in the guideline 1. Before first use, the bottle needs to be primed by pumping 10 times until a fine mist appears, and if the spray hasn't been used for more than 7 days, it should be reprimed with 2 sprays, ensuring proper administration and effectiveness of the medication, as part of the standard instructions for use. Parents should help younger children with administration, ensuring the spray is directed away from the nasal septum to minimize potential side effects, such as headache, viral infection, pharyngitis, epistaxis, and cough, which are commonly associated with the use of Nasonex, as reported in the clinical practice guideline 1.

From the FDA Drug Label

Children age 2 to 11 An adult should supervise use Use one spray in each nostril once daily. The recommended dose of Nasonex (mometasone furoate nasal spray) in children is one spray in each nostril once daily. This should be done under the supervision of an adult. It is also advised to check with the child's doctor if the child needs to use the spray for longer than two months a year 2.

From the Research

Nasonex Dose in Children

  • The recommended dose of Nasonex (mometasone furoate) in children varies depending on the age and condition being treated 3, 4, 5.
  • For children aged 6-11 years with seasonal allergic rhinitis, a dose of 100 micrograms once daily has been shown to be effective and well-tolerated 3.
  • In children with perennial allergic rhinitis, a dose of 100 micrograms once daily has also been shown to be effective and safe for up to 1 year 4, 5.
  • A study in children aged 6-11 years with seasonal allergic rhinitis found that a dose of 100 micrograms once daily was more effective than a dose of 25 micrograms once daily, but not significantly different from a dose of 200 micrograms once daily 3.
  • Another study in children aged 3-11 years with perennial allergic rhinitis found that a dose of 100 micrograms once daily was effective and well-tolerated for up to 6 months 5.

Safety and Tolerability

  • Nasonex has been shown to be well-tolerated in children, with a safety profile similar to placebo 3, 4, 5.
  • The most common adverse events reported in children taking Nasonex include epistaxis, headache, and pharyngitis 4, 5.
  • There is no evidence of systemic effects, such as suppression of the hypothalamic-pituitary-adrenal axis, with the use of Nasonex in children 3, 4.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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