What is the significance of moderate tricuspid regurgitation (TR) in an 81-year-old female (f) patient presenting with dyspnea?

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Differential Diagnosis for 81-year-old Female with Dyspnea and Moderate Tricuspid Regurgitation

  • Single most likely diagnosis:
    • Tricuspid regurgitation due to annular dilation from right ventricular enlargement, often secondary to left-sided heart failure or pulmonary hypertension. This is likely given the patient's age and the presence of moderate tricuspid regurgitation.
  • Other Likely diagnoses:
    • Pulmonary hypertension: Can lead to right ventricular enlargement and subsequent tricuspid regurgitation.
    • Left-sided heart failure: Often causes pulmonary congestion, leading to pulmonary hypertension and right ventricular strain.
    • Cor pulmonale: Right-sided heart failure due to pulmonary disease, which can cause tricuspid regurgitation.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Pulmonary embolism: Although less likely, it can cause acute right ventricular strain and tricuspid regurgitation, and is potentially life-threatening if not promptly diagnosed and treated.
    • Endocarditis of the tricuspid valve: Though uncommon, especially in the absence of other risk factors like intravenous drug use, it's a critical diagnosis not to miss due to its severe consequences.
    • Cardiac tamponade: Can cause dyspnea and might lead to tricuspid regurgitation due to the increased pressure affecting the heart's ability to fill properly.
  • Rare diagnoses:
    • Ebstein's anomaly: A congenital heart defect that affects the tricuspid valve, though it typically presents earlier in life.
    • Carcinoid heart disease: A rare condition where a carcinoid tumor secretes substances that can damage the heart valves, particularly the tricuspid valve.
    • Traumatic tricuspid regurgitation: Could be a consideration if there's a history of chest trauma, but this would be less common in the context provided.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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