What is the likely diagnosis for a 48-year-old male with a firm, non-tender, and mobile lump on the bottom of his right testicle, noticed 1 day ago, with a history of vasectomy (vas deferens ligation)?

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Differential Diagnosis for a Firm Lump on the Bottom of the Right Testicle

Single Most Likely Diagnosis

  • Sperm Granuloma: This is a common complication of vasectomy, occurring in up to 40% of cases. It is a benign condition where a lump forms at the site of the vasectomy due to the body's reaction to sperm. The fact that the lump is firm, mobile, and non-tender, combined with the patient's history of vasectomy, makes this the most likely diagnosis.

Other Likely Diagnoses

  • Epididymal Cyst: A benign fluid-filled cyst that can form on the epididymis, which is located at the back of the testicle. These cysts are common and can be mobile and non-tender, fitting the patient's symptoms.
  • Hydrocele: An accumulation of fluid around a testicle, leading to swelling. While hydroceles are usually more fluid-filled and less firm than the described lump, they can sometimes present as a firm mass, especially if the fluid is located in a specific area.
  • Varicocele: An enlargement of the veins within the scrotum, similar to varicose veins. Varicoceles can feel like a firm, mobile lump and are more common on the left side but can occur on the right.

Do Not Miss Diagnoses

  • Testicular Cancer: Although less likely given the acute onset and the patient's history of vasectomy, testicular cancer must be considered, especially if the lump is solid and non-tender. Missing this diagnosis could have severe consequences, as testicular cancer can progress rapidly.
  • Epididymitis: Inflammation of the epididymis, usually caused by infection. While the patient reports the lump as non-tender, epididymitis can sometimes present with minimal pain, especially in its early stages. It's crucial to consider this diagnosis due to the potential for complications if left untreated.

Rare Diagnoses

  • Adenomatoid Tumor: A rare, benign tumor of the epididymis or testicle. These tumors are usually solid and can be mobile, but they are much less common than other conditions listed here.
  • Lipoma of the Spermatic Cord: A rare, benign tumor composed of fat tissue that can occur in the spermatic cord. It would present as a firm, mobile mass but is relatively uncommon.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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