What is the diagnosis for a male patient presenting with bilateral temporomandibular (TMJ) pain, exacerbated by mouth opening, and experiencing burning, stabbing pain in the cheek?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 20, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Bilateral Jaw Pain and Cheek Pain

  • Single most likely diagnosis
    • Temporomandibular Joint (TMJ) Disorder: The symptoms of bilateral jaw pain, worse with opening the mouth, and burning/stabbing pain in the cheek are classic for TMJ disorder. This condition affects the joint that connects the jawbone to the skull and can cause pain and discomfort in the jaw, face, and surrounding areas.
  • Other Likely diagnoses
    • Bruxism: Grinding or clenching of the teeth can lead to jaw pain, especially if it occurs at night. The pain can radiate to the cheeks and be exacerbated by opening the mouth.
    • Trigeminal Neuralgia: This condition involves sudden, severe, and stabbing pain in parts of the face, which can include the cheeks. Although it typically affects one side of the face, it could potentially cause bilateral pain.
    • Dental Problems: Issues like abscesses, impacted teeth, or gum disease can cause pain in the jaw and cheeks, especially if the problem is severe or widespread.
  • Do Not Miss diagnoses
    • Acute Angle-Closure Glaucoma: Although this condition primarily affects the eyes, it can cause severe pain that radiates to the face, including the cheeks and jaw. It is a medical emergency that requires immediate attention.
    • Giant Cell Arteritis: This condition involves inflammation of the blood vessels and can cause jaw pain, especially when chewing or opening the mouth. It is more common in older adults and can lead to serious complications if left untreated.
    • Osteonecrosis of the Jaw: This rare but serious condition involves the death of bone tissue in the jaw, often due to bisphosphonate use or other medications. It can cause severe pain and requires prompt medical attention.
  • Rare diagnoses
    • Eagle Syndrome: This condition involves an elongated styloid process or calcified stylohyoid ligament, which can cause facial and jaw pain. It is relatively rare and may require specialized imaging to diagnose.
    • Sphenoid Sinusitis: Inflammation or infection of the sphenoid sinus can cause pain in the face, including the cheeks and jaw. It is a rare condition that may require imaging studies to diagnose.
    • Multiple Sclerosis: In some cases, multiple sclerosis can cause facial pain, including pain in the cheeks and jaw, due to demyelination of the trigeminal nerve. However, this would typically be accompanied by other neurological symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.