What is the most likely diagnosis for an 11-year-old boy with hemophilia (hemophilia A) presenting with headaches, declining academic performance, bilateral papilledema, and left-sided hyperreflexia after a traumatic fall?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 21, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis

The patient's presentation of headaches, decreasing school performance, bilateral papilledema, and hyperreflexia after a significant fall suggests a traumatic brain injury. Given the patient's hemophilia A, there is an increased risk of bleeding complications.

  • Single most likely diagnosis

    • E) Subdural hematoma: This is the most likely diagnosis due to the patient's history of trauma, symptoms of increased intracranial pressure (bilateral papilledema), and the presence of hyperreflexia. The initial CT scan may have missed a small subdural hematoma, which can expand over time, especially in a patient with a coagulopathy like hemophilia A.
  • Other Likely diagnoses

    • B) Epidural hematoma: Although less likely than subdural hematoma, epidural hematoma is still a possibility, especially given the mechanism of injury and the patient's coagulopathy. However, epidural hematomas typically present with a loss of consciousness and a more rapid deterioration.
    • C) Postconcussive syndrome: This diagnosis could explain the patient's headaches and decreased school performance but does not account for the bilateral papilledema and hyperreflexia, which suggest increased intracranial pressure.
  • Do Not Miss

    • D) Subarachnoid hemorrhage: Although less likely, subarachnoid hemorrhage is a potentially life-threatening condition that requires prompt diagnosis and treatment. The patient's symptoms and history of trauma make it essential to consider this diagnosis.
    • A) Brain abscess: While brain abscess is unlikely given the acute presentation after trauma, it is a serious condition that could present with increased intracranial pressure and focal neurological signs. However, the history provided does not strongly suggest an infectious process.
  • Rare diagnoses

    • Other rare diagnoses, such as cerebral venous sinus thrombosis or traumatic arteriovenous fistula, could be considered but are less likely given the information provided. These conditions might present with similar symptoms but are less common and would require specific diagnostic testing for confirmation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.