What is the methane dysbiosis score?

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Last updated: February 20, 2025View editorial policy

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From the Research

The methane dysbiosis score is a measure used to assess the level of methane-producing microorganisms in the gut, particularly focusing on methanogens like Methanobrevibacter smithii, with higher scores indicating a greater presence of these organisms associated with certain digestive issues. To address a high methane dysbiosis score, consider the following interventions:

  • A combination of herbal antimicrobials:
    • Allicin (from garlic): 450 mg twice daily
    • Oregano oil: 200 mg three times daily
    • Berberine: 500 mg three times daily Take this combination for 4-6 weeks, as supported by various studies 1, 2, 3, 4, 5.
  • Implement a low FODMAP diet for 2-4 weeks to reduce fermentable carbohydrates that feed methanogens.
  • Supplement with Atrantil: 2 capsules three times daily for 2-4 weeks, which contains quebracho, conker tree, and M. balsamea Willd extracts that can help reduce methane production.
  • Consider adding a prokinetic agent like ginger (500 mg before meals) or low-dose naltrexone (2.5-4.5 mg at bedtime) to improve gut motility, as suggested by studies such as 1 and 5. These interventions target methanogens by directly inhibiting their growth, reducing their food sources, and improving gut motility to prevent their overgrowth. The combination approach is often more effective than single interventions, as shown in studies like 3. After treatment, gradually reintroduce FODMAPs and reassess symptoms. If issues persist, consult a gastroenterologist for further evaluation and potential prescription treatments like rifaximin, which has been shown to be effective in reducing methane production and improving symptoms in patients with methane-positive irritable bowel syndrome 2, 3, 4, 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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