What are the Lites criteria (Liver Injury Test for Early assessment of Severity)?

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Last updated: May 21, 2025View editorial policy

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From the Research

Lumbar puncture should be performed with caution in patients with suspected bacterial meningitis, and the decision to perform a lumbar puncture should be based on a thorough clinical evaluation, including the assessment of signs of impending herniation, such as deteriorating level of consciousness, brainstem signs, and recent seizure, as recommended by the most recent and highest quality study 1.

Clinical Evaluation

When evaluating a patient with suspected bacterial meningitis, it is essential to consider the risk of cerebral herniation, which can be precipitated by lumbar puncture. The clinical signs of impending herniation, such as deteriorating level of consciousness, brainstem signs, and recent seizure, should be carefully assessed 2.

Imaging Studies

While cranial computed tomography (CT) scans can be useful in identifying contraindications to lumbar puncture, a normal CT scan does not necessarily mean that a lumbar puncture is safe 3. The Infectious Diseases Society of America (IDSA) guidelines recommend that cranial imaging be performed before lumbar puncture in patients with suspected bacterial meningitis, especially in those with signs of impending herniation or other risk factors 1.

Management

In patients with suspected bacterial meningitis, the management should focus on controlling intracranial pressure, administering antibiotics, and providing supportive care. Lumbar puncture should only be performed when the benefits outweigh the risks, and the patient's condition is stable enough to undergo the procedure 4.

Key Considerations

  • Clinical evaluation is crucial in assessing the risk of cerebral herniation in patients with suspected bacterial meningitis.
  • Cranial imaging, such as CT scans, can be useful in identifying contraindications to lumbar puncture, but a normal scan does not guarantee safety.
  • The IDSA guidelines provide a framework for managing patients with suspected bacterial meningitis, including the use of cranial imaging and lumbar puncture.
  • The decision to perform a lumbar puncture should be based on a thorough clinical evaluation and consideration of the potential risks and benefits.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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