Can calcipotriene (Dovonex) be used on the face?

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Last updated: May 21, 2025View editorial policy

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From the Guidelines

Dovonex (calcipotriene) can be used on the face, but it is recommended to use it in combination with hydrocortisone to minimize the risk of irritation and other adverse reactions. When considering the use of Dovonex on the face, it is essential to weigh the potential benefits against the potential risks. The facial skin is thinner and more sensitive than skin elsewhere on the body, which increases the risk of irritation, redness, and other adverse reactions when using Dovonex in this area. However, according to a study published in the Journal of the American Academy of Dermatology 1, the use of calcipotriene or tacalcitol ointment combined with hydrocortisone is efficacious for the treatment of facial psoriasis. Some key points to consider when using Dovonex on the face include:

  • The use of combination treatments with vitamin D analogues and potent topical corticosteroids is more effective than either agent alone for the treatment of psoriasis 1.
  • The efficacy of vitamin D analogues was noted at 8 weeks but not at 4 weeks, which can be considered and addressed with patients when planning appropriate topical treatment 1.
  • Topical calcipotriene has displayed greater efficacy than 6% coal tar or salicylic acid but less efficacy than liquor carbonis detergens (LCD) 15% solution 1. It is crucial to consult with a dermatologist before applying any psoriasis medication to the face, as they can recommend the most appropriate treatment based on the specific condition and needs. Alternative treatments, such as low-potency topical corticosteroids, tacrolimus (Protopic), or pimecrolimus (Elidel), may also be considered for facial psoriasis 1.

From the FDA Drug Label

Calcipotriene should not be used on the face. Avoid contact with the face or eyes

  • Dovonex (calcipotriene) should not be used on the face due to potential irritation and other adverse effects 2, 2.

From the Research

Use of Dovonex on the Face

  • There is no direct evidence in the provided studies that specifically addresses the use of Dovonex (calcipotriene) on the face.
  • However, the studies suggest that Dovonex is effective and safe for the treatment of psoriasis in various areas of the body, including the scalp and body 3, 4, 5, 6, 7.
  • It is worth noting that Dovonex can cause skin irritation, which may be a concern when used on sensitive areas such as the face 4, 7.
  • The combination of Dovonex with other topical agents, such as corticosteroids, may help to reduce the risk of skin irritation and improve efficacy 3, 6.

Potential Considerations

  • The safety and efficacy of Dovonex for use on the face would depend on various factors, including the individual's skin type and the severity of their psoriasis.
  • As with any topical treatment, it is essential to follow the recommended usage and dosage instructions to minimize the risk of adverse effects.
  • Further research would be needed to determine the safety and efficacy of Dovonex for use on the face specifically 7.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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