What are the normal values of Complement 3 (C3) and Complement 4 (C4) in a 7-year-old male?

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Last updated: May 21, 2025View editorial policy

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From the Research

The normal values of complement proteins C3 and C4 in a 7-year-old boy are approximately 90-180 mg/dL for C3 and 10-40 mg/dL for C4. These values may vary slightly between different laboratories due to differences in testing methods 1. Complement proteins are important components of the immune system that help fight infections and clear immune complexes. C3 and C4 levels are often measured to evaluate immune function and to diagnose or monitor certain conditions such as lupus, glomerulonephritis, or immunodeficiency disorders.

  • Low levels of these proteins may indicate ongoing inflammation, autoimmune disease, or complement consumption due to immune complex formation.
  • It's essential to interpret these values in the clinical context of the child's symptoms and other laboratory findings.
  • If abnormal values are found, repeat testing may be necessary, and consultation with a pediatric immunologist or rheumatologist might be warranted depending on the clinical scenario 2, 3. The provided studies, although informative about complement deficiencies and related disorders, do not directly address the normal values of C3 and C4 in a healthy 7-year-old boy. However, based on general medical knowledge and the information given, the normal ranges for C3 and C4 can be applied to guide clinical decision-making.

References

Research

Complement C4, Infections, and Autoimmune Diseases.

Frontiers in immunology, 2021

Research

C3 Glomerulopathy and Related Disorders in Children: Etiology-Phenotype Correlation and Outcomes.

Clinical journal of the American Society of Nephrology : CJASN, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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