Is cryotherapy appropriate for removing an acrochordon (skin tag)?

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Last updated: May 21, 2025View editorial policy

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From the Research

Cryotherapy is an appropriate and effective method for removing skin tags, with a high success rate and minimal side effects, as demonstrated by the most recent and highest quality study 1.

Key Points to Consider

  • Cryotherapy involves freezing the skin tag with liquid nitrogen, which destroys the tissue and causes it to fall off within a few days to weeks after treatment.
  • The process typically takes only a few minutes in a healthcare provider's office and requires no special preparation.
  • Patients may feel a brief stinging or burning sensation during application, and the area may blister, turn red, or become slightly swollen before the skin tag darkens and eventually falls off.
  • Most skin tags require only one treatment session, though larger ones might need repeat applications.
  • Cryotherapy is preferred for skin tag removal because it's quick, minimally invasive, leaves little to no scarring, and has a high success rate, with 64.3% of skin tags completely disappearing during the study 2.

Important Considerations

  • It's essential to have a healthcare provider confirm that the growth is indeed a benign skin tag before proceeding with any removal method.
  • While electrosurgery may be more effective for certain skin conditions, such as sebaceous hyperplasia and cherry angioma, cryotherapy is still a viable option for skin tag removal 1.
  • The safety and efficacy of cryotherapy have been demonstrated in various studies, including a prospective, single-blinded, randomized, comparative clinical trial 2.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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