What are the dosing recommendations for Guaifenesin (Mucinex) and Guaifenesin and Dextromethorphan (Mucinex DM)?

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Last updated: May 21, 2025 • View editorial policy

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From the FDA Drug Label

Guaifenesin Oral Solution USP is a red, raspberry flavored solution supplied in the following oral dosage forms: NDC 0121-0744-04: 4 fl oz (120 mL) bottle NDC 0121-0744-08: 8 fl oz (237 mL) bottle NDC 0121-0744-16: 16 fl oz (473 mL) bottle NDC 0121-1744-05: 5 mL unit dose cup NDC 0121-1744-00: Case contains 100 unit dose cups of 5 mL (0121-1744-05) packaged in 10 trays of 10 unit dose cups each. NDC 0121-1488-10: 10 mL unit dose cup NDC 0121-1488-00: Case contains 100 unit dose cups of 10 mL (0121-1488-10) packaged in 10 trays of 10 unit dose cups each. NDC 0121-2232-15: 15 mL unit dose cup NDC 0121-2232-00: Case contains 100 unit dose cups of 15 mL (0121-2232-15) packaged in 10 trays of 10 unit dose cups each.

The dose of Mucinex is not explicitly stated in the provided drug labels. However, the labels do provide information on the available dosage forms and concentrations of guaifenesin, which is the active ingredient in Mucinex.

  • The concentration of guaifenesin in the oral solution is 200 mg/10 mL 1 and 300 mg/15 mL 1. The FDA drug label does not provide a specific dose for Mucinex or Mucinex DM.

References

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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