What is the dosing regimen for Norethindrone (a progestin) to delay menstruation?

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From the FDA Drug Label

To achieve maximum contraceptive effectiveness, norethindrone tablets must be taken exactly as directed. One tablet is taken every day, at the same time. Administration is continuous, with no interruption between pill packs.

The FDA drug label does not answer the question.

From the Research

Norethindrone can be used to delay a period by taking 5 mg three times daily, starting on or before cycle day 12, as it has been shown to be superior to combined oral contraceptive pills in short-term delay of menses and onset of breakthrough bleeding 1. To delay a period, norethindrone can be taken at a dose of 5 mg three times daily, with the goal of maintaining the uterine lining and preventing it from shedding.

  • The medication should be started on or before cycle day 12 to be effective in delaying menstruation.
  • Once the medication is stopped, the period will typically start within 2-3 days.
  • It is essential to note that this regimen should not be continued for more than 2-3 weeks without medical supervision. Some potential side effects of norethindrone include:
  • Breakthrough bleeding
  • Breast tenderness
  • Nausea
  • Headaches
  • Mood changes Norethindrone works by providing a continuous level of progestin, which maintains the uterine lining and prevents it from shedding.
  • This medication requires a prescription, so it is necessary to consult with a healthcare provider before using it.
  • While norethindrone can delay menstruation, it is not a contraceptive at this dosage, so additional birth control methods should be used if pregnancy prevention is desired. If severe side effects occur, such as abdominal pain, chest pain, severe headaches, vision changes, or signs of blood clots, it is crucial to seek medical attention immediately 1.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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