What is the differential diagnosis (Ddx) of syndesmophytes?

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Differential Diagnosis for Syndesmophytes

  • Single most likely diagnosis
    • Ankylosing Spondylitis (AS): This is the most common cause of syndesmophytes, which are a type of bony growth that can occur in the spine. AS is a chronic inflammatory disease that affects the joints and spine, leading to the formation of syndesmophytes.
  • Other Likely diagnoses
    • Psoriatic Arthritis (PsA): This condition can also cause syndesmophytes, although they are less common than in AS. PsA is a type of arthritis that occurs in people with psoriasis, and it can cause inflammation and damage to the joints and spine.
    • Reactive Arthritis: This condition can cause syndesmophytes, especially in the lower back. Reactive arthritis is a type of arthritis that occurs in response to an infection, often in the gastrointestinal tract or the urinary tract.
    • Spondyloarthritis: This is a group of conditions that includes AS, PsA, and reactive arthritis, among others. Spondyloarthritis can cause syndesmophytes, as well as other types of spinal abnormalities.
  • Do Not Miss diagnoses
    • Diffuse Idiopathic Skeletal Hyperostosis (DISH): This condition can cause syndesmophytes, as well as other types of bony growths. DISH is a condition that affects the spine and other joints, and it can cause significant disability if left untreated.
    • Osteophytosis: This condition can cause bony growths that resemble syndesmophytes. Osteophytosis is a condition that affects the spine and other joints, and it can cause pain and stiffness.
  • Rare diagnoses
    • Spondyloepiphyseal Dysplasia: This is a rare genetic condition that can cause syndesmophytes, as well as other types of spinal abnormalities. Spondyloepiphyseal dysplasia is a condition that affects the development of the spine and other joints.
    • Hyperparathyroidism: This condition can cause an overproduction of parathyroid hormone, which can lead to the formation of syndesmophytes. Hyperparathyroidism is a rare condition that can cause a range of symptoms, including bone pain and weakness.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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