What causes ulcers on the fingertips, also known as digital (finger) ulcers?

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Last updated: May 21, 2025View editorial policy

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Differential Diagnosis for Ulcers at Fingertips

  • Single most likely diagnosis
    • Raynaud's phenomenon: This condition is characterized by a sudden and temporary narrowing of the arteries, leading to reduced blood flow to the fingers and toes. It can cause ulcers at the fingertips due to the lack of oxygen and nutrients.
  • Other Likely diagnoses
    • Trauma: Direct injury to the fingertips can cause ulcers, especially if the wound becomes infected.
    • Vasculitis: Inflammation of the blood vessels can lead to ulcers at the fingertips, particularly in conditions like lupus or rheumatoid arthritis.
    • Diabetic neuropathy: Nerve damage in people with diabetes can lead to loss of sensation in the fingers, making it difficult to notice injuries or pressure points that can cause ulcers.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Sepsis: Bacterial infections, such as those caused by Streptococcus or Staphylococcus, can lead to sepsis, a life-threatening condition that requires prompt treatment.
    • Gangrene: Reduced blood flow to the fingertips can cause gangrene, a condition where tissue dies due to lack of oxygen and nutrients.
    • Malignancy: In rare cases, ulcers at the fingertips can be a sign of an underlying malignancy, such as squamous cell carcinoma.
  • Rare diagnoses
    • Buerger's disease: A rare condition characterized by inflammation of the blood vessels, which can lead to ulcers at the fingertips.
    • Scleroderma: A chronic autoimmune disease that can cause thickening of the skin and reduced blood flow, leading to ulcers at the fingertips.
    • Chilblains: A condition caused by prolonged exposure to cold temperatures, leading to inflammation of the small blood vessels and ulcers at the fingertips.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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