From the Guidelines
The brand name of chlordiazepoxide is Librium. Chlordiazepoxide is a benzodiazepine medication primarily used to treat anxiety disorders and alcohol withdrawal symptoms. It works by enhancing the effect of the neurotransmitter GABA in the brain, which produces a calming effect. According to the American Academy of Sleep Medicine clinical practice guideline 1, the first benzodiazepine, chlordiazepoxide, was introduced to the United States market in 1963. While Librium remains the most recognized brand name, chlordiazepoxide may also be marketed under other brand names in different countries. Some key points to consider when prescribing chlordiazepoxide include:
- Dependence and potential for abuse, so it's typically prescribed for short-term use
- Common side effects include drowsiness, coordination problems, and confusion, particularly in elderly patients
- History of use as a hypnotic alternative to barbiturates and similar compounds for treatment of insomnia, although it has largely been supplanted by other medications such as zolpidem and eszopiclone. It is essential to weigh the benefits and risks of chlordiazepoxide, considering its potential for dependence and side effects, especially in vulnerable populations like the elderly 1.
From the Research
Brand Name of Chlordiazepoxide
- The brand name of chlordiazepoxide is Librium® 2, 3
- Chlordiazepoxide was initially called methaminodiazepoxide and was introduced in clinical treatment in 1960 under the brand name Librium® 2
- Librium® is a benzodiazepine that was the first of its class to be introduced, and it has been used to treat anxiety disorders and alcohol withdrawal syndrome 2, 4