Are brisk reflexes associated with Multiple Sclerosis (MS)?

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Last updated: February 21, 2025View editorial policy

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From the Research

Brisk reflexes can be a sign of Multiple Sclerosis (MS), as they are often accompanied by other upper motor neuron signs such as spasticity, weakness, and Babinski sign, as observed in a patient with MS who presented with brisk deep tendon reflexes on the left upper limb 1. In MS, the myelin sheath that covers nerve fibers in the central nervous system is damaged, leading to interruption of normal nerve signal transmission, resulting in various neurological symptoms, including changes in reflexes. Some key points to consider include:

  • Brisk reflexes in MS are not specific to the condition and can occur in other neurological disorders as well 2, 3.
  • A comprehensive neurological examination and additional diagnostic tests (like MRI) are necessary for an accurate MS diagnosis 1, 4.
  • Spasticity is a prevalent and troublesome symptom for people with MS, and its assessment should incorporate the patient's perspective 4.
  • The management of MS symptoms, including spasticity, is crucial to improve patient autonomy, quality of life, and reduce health resource utilization and costs 2, 3, 4. If you notice changes in your reflexes or other neurological symptoms, it is essential to consult a neurologist for proper evaluation and management.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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