What is the function of BPC-157 (Body Protection Compound-157), a gastric pentadecapeptide?

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Last updated: May 22, 2025View editorial policy

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From the Research

Gastric Pentadecapeptide BPC-157 is a synthetic peptide with potential healing properties, promoting tissue repair, reducing inflammation, and protecting organs, as evidenced by the most recent study in 2024 1.

Introduction to BPC-157

BPC-157 is a 15-amino acid peptide derived from a protective protein found in gastric juice, with potential applications in wound healing, inflammation reduction, and organ protection.

Mechanism of Action

The compound may influence growth factors, collagen formation, and nitric oxide pathways to achieve its effects, as suggested by studies on its relation to the NO-system 2.

Potential Applications

BPC-157 has been researched for its potential to counteract NSAIDs toxicity 3, promote angiogenesis, and support gut health, with potential benefits in various tissues, including the stomach, duodenum, intestine, liver, and brain.

Current Status and Recommendations

Given the limited human evidence and lack of FDA approval, BPC-157 should be considered an experimental compound, and its use should be approached with caution, consulting a healthcare provider before administration 1. Some key points to consider:

  • BPC-157 is not FDA-approved for human use
  • Limited scientific evidence in humans is available
  • Potential risks and unknown long-term effects exist
  • Consulting a healthcare provider before using BPC-157 is strongly recommended

Dosage and Administration

Typical doses range from 200-500 micrograms, administered via subcutaneous injection, oral consumption, or topical application, with treatment durations commonly ranging from 1-4 weeks, as reported in various studies 4, 5.

Future Directions

Further research is needed to fully understand the potential benefits and risks of BPC-157, as well as its mechanisms of action, to determine its potential as a therapeutic agent, as highlighted in recent reviews 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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