From the Guidelines
Unconventional methods being investigated to increase testosterone levels include lifestyle modifications, such as weight loss and increased physical activity, as well as alternative therapies like red light therapy and boron supplementation. According to the American Urological Association guideline 1, lifestyle modifications, such as losing weight or maintaining weight within the recommended range, along with increasing physical activity, have the potential to increase total testosterone levels and/or reduce signs and symptoms associated with testosterone deficiency.
Some less common approaches being explored to boost testosterone include:
- Red light therapy: Daily exposure of testicles to red/near-infrared light for 10-20 minutes may increase testosterone production, as suggested by recent studies 1.
- Boron supplementation: Taking 6-10 mg of boron daily for 1-2 months may modestly increase free testosterone levels by reducing sex hormone binding globulin, as reported in a study published in the Journal of Urology 1.
- Ashwagandha: Consuming 300-600 mg of a high-quality extract daily for 8-12 weeks may boost testosterone, likely by reducing cortisol and stress, although more research is needed to confirm this effect 1.
- Cold water immersion: Brief full-body exposure to cold water (50-59°F) for 2-3 minutes, 2-3 times per week, may acutely increase testosterone, as suggested by a study published in the Annals of Internal Medicine 1.
- Pulsed electromagnetic field therapy: Using PEMF devices on the groin area for 15-30 minutes daily may stimulate Leydig cell function, although more research is needed to confirm this effect.
- Nasal testosterone gels: Applying testosterone gel intranasally is being studied as an alternative to injections or transdermal applications for testosterone replacement therapy, as reported in a study published in the Journal of Urology 1.
These methods are still being researched and may not be as well-established as traditional approaches like weight training, proper nutrition, and adequate sleep. Consult a healthcare provider before trying any new testosterone-boosting regimen, especially if considering supplements or therapies that could affect hormone levels.
From the Research
Unconventional Methods for Increasing Testosterone Levels
Some unconventional methods being investigated to increase testosterone levels include:
- The use of selective estrogen receptor modulators, gonadotropins, and aromatase inhibitors to increase endogenous testosterone levels while preserving fertility and function of the HPG axis 2
- The off-label use of human chorionic gonadotropin (hCG) and anastrozole inhibitors to treat hypogonadal symptoms while increasing intratesticular testosterone 3
- The use of Natesto intranasal testosterone gel, which has been shown to increase serum testosterone levels while maintaining semen parameters 3
- Nonpharmacologic interventions such as:
- Nutraceuticals and functional nutrients like zinc, vitamin D, l-arginine, mucuna, and ashwagandha 4
- Lifestyle modifications including adequate sleep, exercise, and weight loss in patients with obesity 4
- Dietary changes, such as the use of tribulus and ω3 fatty acids, which can improve some degree of sperm parameters in infertile men 4
Limitations and Considerations
It is essential to note that:
- The effects of nonpharmacologic interventions on testosterone levels are modest and may not directly translate into clinical benefits 4
- Many "testosterone boosting" supplements have unsupported claims and may contain supra-therapeutic doses of vitamins and minerals, occasionally exceeding the upper tolerable intake level (UL) 5
- Patients should be informed that "testosterone booster" supplements may not have ingredients to support their claims, and only a limited number of supplements have data showing an increase in testosterone with supplementation 5