Differential Diagnoses for Each Case
Case 1: Child with Sore Throat, Jaundice, and Hepatosplenomegaly
- Single Most Likely Diagnosis: Infectious Mononucleosis (EBV) - justified by the combination of sore throat, jaundice, hepatosplenomegaly, and the child feeling tired.
- Other Likely Diagnoses:
- Viral Hepatitis - could explain jaundice and hepatosplenomegaly.
- Toxoplasmosis - might cause similar symptoms in immunocompromised individuals.
- Do Not Miss Diagnoses:
- Leukemia - although less likely, it's crucial to rule out due to its severe implications.
- Sickle Cell Disease - could cause hepatosplenomegaly and other systemic symptoms.
- Rare Diagnoses:
- Lymphoma - a rare cause of hepatosplenomegaly and systemic symptoms.
- Autoimmune Hemolytic Anemia - could explain jaundice and hepatosplenomegaly.
Case 2: Video of a Patient with Borderline Personality Disorder
- Single Most Likely Diagnosis: Borderline Personality Disorder - based on the video presentation.
- Other Likely Diagnoses:
- Histrionic Personality Disorder - shares some similarities with borderline personality disorder.
- Post-Traumatic Stress Disorder (PTSD) - could be a comorbid condition.
- Do Not Miss Diagnoses:
- Bipolar Disorder - important to differentiate due to treatment implications.
- Substance Use Disorder - could mimic or complicate borderline personality disorder.
- Rare Diagnoses:
- Factitious Disorder - a rare condition where a person acts as if they have an illness.
- Dissociative Identity Disorder - although rare, it might present with similar symptoms.
Case 3: Patient with GCS 10
- Single Most Likely Diagnosis: Traumatic Brain Injury - given the low GCS score.
- Other Likely Diagnoses:
- Stroke - could cause altered mental status and low GCS.
- Metabolic Encephalopathy - various metabolic issues could lead to a decreased level of consciousness.
- Do Not Miss Diagnoses:
- Status Epilepticus - a medical emergency that requires immediate intervention.
- Meningitis/Encephalitis - infections that could cause severe neurological symptoms.
- Rare Diagnoses:
- Brain Tumor - although rare, it could cause increased intracranial pressure and low GCS.
- Subarachnoid Hemorrhage - a severe condition with high morbidity and mortality.
Case 4: Erectile Dysfunction
- Single Most Likely Diagnosis: Vasculogenic Erectile Dysfunction - given the patient's age and late working hours.
- Other Likely Diagnoses:
- Psychogenic Erectile Dysfunction - stress and relationship issues could contribute.
- Neurogenic Erectile Dysfunction - possible if there are underlying neurological conditions.
- Do Not Miss Diagnoses:
- Hypogonadism - low testosterone levels could cause erectile dysfunction.
- Peyronie's Disease - a condition that causes curved, painful erections.
- Rare Diagnoses:
- Priapism - a rare condition where erections are prolonged and painful.
- Penile Fracture - a rare injury that could cause erectile dysfunction.
Case 5: Asthma Action Plan
- This case does not require a differential diagnosis as it involves explaining and demonstrating the use of an asthma action plan and spacer.
Case 6: Patient with Known BMD Under Lithium
- Single Most Likely Diagnosis: Bipolar Disorder (BMD) - as stated in the scenario.
- Other Likely Diagnoses:
- Schizoaffective Disorder - could be considered if there are psychotic symptoms.
- Major Depressive Disorder - might be a comorbid condition.
- Do Not Miss Diagnoses:
- Lithium Toxicity - a serious condition that requires immediate attention.
- Thyroid Dysfunction - lithium can affect thyroid function.
- Rare Diagnoses:
- Cyclic Mood Disorder - a rare condition characterized by rapid cycling of mood symptoms.
- Schizophrenia - although less likely, it's essential to rule out due to treatment implications.
Case 7: 9-Month-Old Child with Weight Concerns
- Single Most Likely Diagnosis: Failure to Thrive - given the child's weight and age.
- Other Likely Diagnoses:
- Gastroesophageal Reflux Disease (GERD) - could cause feeding difficulties and weight loss.
- Lactose Intolerance - might lead to malabsorption and failure to thrive.
- Do Not Miss Diagnoses:
- Celiac Disease - an autoimmune disorder that causes malabsorption.
- Congenital Heart Disease - could lead to failure to thrive due to increased metabolic demand.
- Rare Diagnoses:
- Prader-Willi Syndrome - a rare genetic disorder that causes failure to thrive and other systemic symptoms.
- Williams Syndrome - a genetic disorder that could cause failure to thrive and developmental delays.
Case 8: Daughter Admitted with BMD
- Single Most Likely Diagnosis: Bipolar Disorder (BMD) - as stated in the scenario.
- Other Likely Diagnoses:
- Borderline Personality Disorder - might be considered if there are impulsivity and emotional dysregulation.
- Schizoaffective Disorder - could be a differential if there are psychotic symptoms.
- Do Not Miss Diagnoses:
- Substance-Induced Psychotic Disorder - important to rule out due to treatment implications.
- Postpartum Psychosis - if the daughter has recently given birth.
- Rare Diagnoses:
- Brief Psychotic Disorder - a rare condition characterized by a short duration of psychotic symptoms.
- Cyclothymic Disorder - a rare mood disorder with periods of hypomania and depression.
Case 9: 36-Week Pregnant Woman with Itchy Lower Abdomen
- Single Most Likely Diagnosis: Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP) - given the itchy rash in the lower abdomen during pregnancy.
- Other Likely Diagnoses:
- Intrahepatic Cholestasis of Pregnancy (ICP) - could cause itching without a rash.
- Polymorphic Eruption of Pregnancy (PEP) - a condition that causes a rash and itching.
- Do Not Miss Diagnoses:
- Pemphigoid Gestationis - a rare autoimmune disorder that causes blistering and itching.
- Cholestasis due to other causes - important to rule out due to potential fetal risks.
- Rare Diagnoses:
- Prurigo of Pregnancy - a rare condition characterized by itchy nodules.
- Atopic Eruption of Pregnancy - a rare condition with itchy, eczematous lesions.
Case 10: Young Male with Pain in Left Leg on Walking
- Single Most Likely Diagnosis: Intermittent Claudication - given the pain in the leg on walking.
- Other Likely Diagnoses:
- Deep Vein Thrombosis (DVT) - could cause leg pain and swelling.
- Peripheral Artery Disease (PAD) - might cause claudication and leg pain.
- Do Not Miss Diagnoses:
- Pulmonary Embolism - a medical emergency that requires immediate attention.
- Aortic Dissection - a severe condition with high morbidity and mortality.
- Rare Diagnoses:
- Buerger's Disease - a rare condition that causes inflammation and clots in blood vessels.
- Popliteal Artery Entrapment Syndrome - a rare condition that causes leg pain and claudication.
Case 11: Young Male with Left Submandibular Lymph Node Pain
- Single Most Likely Diagnosis: Infectious Mononucleosis (EBV) - given the lymph node pain and potential for sore throat.
- Other Likely Diagnoses:
- Bacterial Pharyngitis - could cause lymph node pain and sore throat.
- Dental Abscess - might cause localized lymph node pain.
- Do Not Miss Diagnoses:
- Tuberculosis (TB) - important to rule out due to public health implications.
- Lymphoma - a rare but serious condition that requires prompt diagnosis.
- Rare Diagnoses:
- Cat-Scratch Disease - a rare condition that causes lymph node pain and swelling.
- Kikuchi-Fujimoto Disease - a rare condition that causes lymph node pain and fever.
Case 12: Young Lady Starting a New Relationship
- This case does not require a differential diagnosis as it involves taking a history and advising on testing for sexually transmitted infections (STIs).
Case 13: 82-Year-Old Lady with Hip Surgery and T10 >20% Wedge Fractures
- Single Most Likely Diagnosis: Osteoporosis - given the wedge fractures and age.
- Other Likely Diagnoses:
- Osteopenia - might be considered if bone density is lower than normal but not osteoporotic.
- Vertebral Compression Fracture - could be caused by osteoporosis or trauma.
- Do Not Miss Diagnoses:
- Multiple Myeloma - a rare condition that causes bone lesions and fractures.
- Metastatic Cancer - important to rule out due to treatment implications.
- Rare Diagnoses:
- Osteogenesis Imperfecta - a rare genetic disorder that causes brittle bones.
- Fibrous Dysplasia - a rare condition that causes bone lesions and fractures.
Case 14: Eye Examination
- This case does not provide enough information for a differential diagnosis.
Case 15: Old Lady with Fracture of the Head of Femur and Cognitive Impairment
- Single Most Likely Diagnosis: Dementia - given the cognitive impairment.
- Other Likely Diagnoses:
- Delirium - might be considered if there are acute changes in mental status.
- Depression - could cause cognitive impairment and functional decline.
- Do Not Miss Diagnoses:
- Normal Pressure Hydrocephalus (NPH) - a rare condition that causes cognitive decline and gait disturbances.
- Chronic Subdural Hematoma - a serious condition that requires prompt diagnosis and treatment.
- Rare Diagnoses:
- Creutzfeldt-Jakob Disease - a rare prion disease that causes rapid cognitive decline.
- Frontotemporal Dementia - a rare condition that causes cognitive and behavioral changes.