What is the diagnosis for Left Ventricular Hypertrophy (LVH) with a prolonged PR interval and diffuse ST segment elevation?

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Differential Diagnosis for LVH with PR Interval Greater than 200 and Diffuse ST Elevation

  • Single Most Likely Diagnosis
    • Hypertrophic Cardiomyopathy (HCM): This condition is characterized by left ventricular hypertrophy (LVH) and can lead to abnormal PR intervals due to the altered cardiac conduction pathways. Diffuse ST elevation can be seen in HCM due to the abnormal ventricular repolarization.
  • Other Likely Diagnoses
    • Left Ventricular Hypertrophy (LVH) with Left Bundle Branch Block (LBBB): LVH can cause ST elevation, and a PR interval greater than 200 can be seen in the context of LBBB, which affects the conduction system of the heart.
    • Cardiac Amyloidosis: This condition can cause LVH and abnormal conduction, leading to prolonged PR intervals. ST elevation can be seen due to the restrictive cardiomyopathy associated with amyloidosis.
  • Do Not Miss Diagnoses
    • Acute Pericarditis: Although less likely, acute pericarditis can cause diffuse ST elevation and can be associated with PR interval prolongation in some cases. Missing this diagnosis could lead to delayed treatment and potential complications.
    • Acute Coronary Syndrome (ACS): While ACS typically presents with more localized ST elevation, it is crucial not to miss this diagnosis, as timely intervention is critical for patient outcomes.
  • Rare Diagnoses
    • Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC): This rare condition can cause abnormal cardiac conduction and repolarization, leading to ST elevation and PR interval prolongation, although it is less commonly associated with LVH.
    • Friedreich's Ataxia: A rare genetic disorder that can cause hypertrophic cardiomyopathy, leading to LVH, and can also affect the cardiac conduction system, resulting in abnormal PR intervals and ST elevation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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