Which vaccine is associated with the development of autism?

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Last updated: February 21, 2025View editorial policy

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From the Guidelines

No vaccines are associated with the development of autism, and the claim that they are is a thoroughly debunked conspiracy theory with no scientific basis. Extensive research, including a review of public health and online misinformation [ 1 ], has found no link between vaccines and autism. The original study claiming a link between the measles, mumps, rubella (MMR) vaccine and autism was found to be fraudulent and was retracted [ 1 ]. Additionally, studies have shown that vaccines are safe and effective at preventing serious diseases, and that claims of a link between vaccines and autism have no scientific basis [ 1 ]. Autism is a complex developmental condition that begins before birth, not something caused by vaccines [ 1 ]. Parents should follow recommended vaccine schedules to protect their children's health. Some key points to consider include:

  • The lack of scientific evidence supporting a link between vaccines and autism [ 1 ]
  • The importance of following recommended vaccine schedules to protect children's health
  • The need to be aware of and critical of online misinformation regarding vaccine safety and efficacy [ 1 ]
  • The complex neurobiology of autism, which suggests that it is a developmental condition that begins before birth, and is not caused by vaccines [ 1 ]

From the Research

Vaccine Association with Autism

  • There is no evidence to support a causal association between any vaccine and the development of autism 2, 3, 4, 5, 6
  • The measles-mumps-rubella (MMR) vaccine has been specifically studied, and no link has been found between MMR vaccination and autism 2, 5, 6
  • The hypothesis that vaccines, including those containing mercury, cause autism has been well researched and refuted 4, 6
  • Epidemiologic studies have found no evidence of a phenotypically distinct form of autism in children who received the MMR vaccine or of a clustering of onset symptoms in children who are autistic after receiving the MMR vaccine 5
  • The biological plausibility of a causal relationship between MMR vaccines and autism remains questionable, and there is a sound body of epidemiological evidence to refute the hypothesis 6

Key Findings

  • Studies have consistently shown that childhood vaccination is not a cause of the sharp increase in autism diagnoses in recent decades 3, 4
  • The etiology of autism is still unknown, with research continuing from different directions 4
  • Despite the overwhelming data demonstrating that there is no link between vaccines and autism, many parents are hesitant to immunize their children because of the alleged association 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

The myth of vaccination and autism spectrum.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2022

Research

Measles-mumps-rubella vaccine and the development of autism.

Seminars in pediatric infectious diseases, 2003

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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