What is the differential diagnosis for acholic stool (white stool)?

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White Stool Differential Diagnosis

The differential diagnosis for white stool can be organized into the following categories:

  • Single Most Likely Diagnosis

    • Biliary obstruction: This is the most likely diagnosis, as white stool (acholic stool) is a common symptom of biliary obstruction, which prevents bile from reaching the intestines, resulting in stool that is pale or clay-colored.
  • Other Likely Diagnoses

    • Pancreatic insufficiency: This condition can lead to malabsorption of fats, resulting in pale, greasy stools.
    • Giardiasis: Infection with Giardia lamblia can cause malabsorption and lead to pale, fatty stools.
    • Celiac disease: This autoimmune disorder can cause malabsorption and lead to pale, greasy stools.
  • Do Not Miss Diagnoses

    • Hepatocellular carcinoma: Although less common, hepatocellular carcinoma can cause biliary obstruction, leading to white stool. Missing this diagnosis could be deadly.
    • Pancreatic cancer: Pancreatic cancer can also cause biliary obstruction, leading to white stool. Early detection is crucial for treatment.
    • Sclerosing cholangitis: This rare condition can cause biliary obstruction and lead to white stool. Missing this diagnosis could result in severe complications.
  • Rare Diagnoses

    • Alagille syndrome: A rare genetic disorder that affects the liver and can cause biliary obstruction, leading to white stool.
    • Biliary atresia: A rare condition in which the bile ducts are blocked or absent, leading to white stool.
    • Caroli's disease: A rare congenital disorder that affects the bile ducts and can cause biliary obstruction, leading to white stool.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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