What is the next step in managing a 32-year-old pregnant woman at 24 weeks gestation presenting with acute onset of abdominal pain, fever, vomiting, and leukocytosis (elevated White Blood Cell count), with normal fetal monitoring and no vaginal bleeding?

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Last updated: May 22, 2025View editorial policy

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From the Guidelines

The next step in management for this 32-year-old pregnant woman at 24 weeks with acute abdominal pain should be abdominal ultrasound (option A). Given her presentation with acute onset epigastric pain that has become diffuse, fever, vomiting, and abdominal tenderness with guarding, urgent evaluation is needed while considering both maternal and fetal well-being. Abdominal ultrasound is the preferred initial imaging modality in pregnancy as it avoids radiation exposure, can visualize many intra-abdominal pathologies (such as appendicitis, cholecystitis, or other surgical emergencies), and can simultaneously assess fetal status, as supported by the American College of Radiology Appropriateness Criteria 1. CT scanning (option B) should be avoided if possible due to radiation exposure to the fetus, although it may be useful in certain cases where ultrasound is inconclusive, as noted in a study by Poletti et al 1. While observation (option C) might be reasonable in milder cases, the presence of diffuse guarding suggests peritoneal irritation requiring immediate diagnostic clarification. Exploratory laparoscopy (option D) is too invasive as a first step before attempting non-invasive diagnostic methods. The ultrasound findings will guide further management decisions, which may ultimately include surgery if an acute surgical condition is identified, and recent guidelines support the use of ultrasound as the initial imaging modality in pregnant women with suspected appendicitis or other acute abdominal conditions 1. Key considerations in the management of this patient include:

  • Avoiding radiation exposure to the fetus whenever possible
  • Promptly identifying and treating any underlying surgical conditions
  • Carefully monitoring fetal well-being throughout the diagnostic and treatment process
  • Considering the potential benefits and risks of different imaging modalities, including ultrasound, CT, and MRI, as outlined in recent studies and guidelines 1.

From the Research

Next Steps in Management

The patient presents with acute onset of abdominal pain, fever, and vomiting, which suggests an acute abdominal condition. Given the patient's pregnancy status, it is essential to consider the safest and most effective diagnostic approach.

  • The patient's symptoms and physical examination findings, such as diffuse tenderness and guarding, indicate the need for further evaluation.
  • The abdominal X-ray series showed dilated bowel loops, which may suggest a bowel obstruction or other abdominal pathology.

Diagnostic Considerations

  • Abdominal ultrasound is a non-invasive and safe diagnostic tool that can be used to evaluate the patient's symptoms, as stated in 2, 3, 4, 5.
  • Ultrasound is particularly useful in pregnant patients, as it does not involve radiation, as mentioned in 3, 4.
  • The patient's presentation and laboratory findings, such as an elevated white blood cell count, suggest an infectious or inflammatory process, which can be further evaluated with ultrasound.

Recommended Course of Action

  • Given the patient's symptoms and physical examination findings, an abdominal ultrasound (Option A) is the most appropriate next step in management, as supported by 2, 3, 4, 5.
  • This diagnostic approach will help to identify potential causes of the patient's symptoms, such as appendicitis, bowel obstruction, or other abdominal pathology, as discussed in 3, 4, 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Abdominal ultrasound.

Annals of emergency medicine, 1986

Research

Imaging acute appendicitis: state of the art.

Journal of clinical imaging science, 2011

Research

Imaging of appendicitis in adults.

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2014

Research

[Abdominal ultrasound in emergency and critical care medicine].

Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2019

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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