What is the cause of whitish smegma (secretion) behind the foreskin and under/along the glans corona?

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Last updated: May 22, 2025View editorial policy

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Differential Diagnosis for Whitish Smegma behind Foreskin and under/along Glans Corona

  • Single most likely diagnosis
    • Smegma: This is the most likely diagnosis due to the description of whitish material behind the foreskin and under/along the glans corona, which is a common location for smegma accumulation. Smegma is a natural, cheesy substance produced by the genital glands.
  • Other Likely diagnoses
    • Balanitis: Inflammation of the glans penis, which can cause a whitish discharge and may be associated with poor hygiene, leading to smegma accumulation.
    • Candidiasis (yeast infection): Can cause a white, cheesy discharge and may be found under the foreskin or on the glans penis.
    • Seborrheic dermatitis: A skin condition that can cause a white, flaky substance to form on the penis, including under the foreskin and on the glans.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Squamous cell carcinoma: Although rare, this type of cancer can present with a white, cheesy discharge and should not be missed due to its potential severity.
    • Gangrene: In rare cases, poor hygiene and smegma accumulation can lead to gangrene, which is a life-threatening condition.
  • Rare diagnoses
    • Lichen sclerosis: A rare skin condition that can cause white, patchy lesions on the penis, including under the foreskin and on the glans.
    • Leukoplakia: A rare condition characterized by white patches on the mucous membranes, including the glans penis.
    • Vitiligo: A rare skin condition that can cause white patches on the penis, although it is not typically associated with a cheesy discharge.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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