What is the cause of severe pruritus (itching) in the axillary (armpit) area, bilaterally, that exacerbates with increased temperature?

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Differential Diagnosis for Severe Itching in Armpit Area

Single Most Likely Diagnosis

  • Eczema (Atopic Dermatitis): This is a common condition characterized by itchy, inflamed skin. The armpits are a common area for eczema to occur, and symptoms can worsen with heat and sweating.

Other Likely Diagnoses

  • Contact Dermatitis: This is a type of skin inflammation caused by contact with irritants or allergens, such as deodorants, soaps, or fabrics. The armpits are a common area for contact dermatitis to occur.
  • Fungal Infections (Intertrigo): Fungal infections can cause itching, redness, and inflammation in the armpits, especially in warm weather.
  • Sweat Gland Disorders (Hyperhidrosis): Excessive sweating can lead to itching, irritation, and skin infections in the armpits.
  • Keratosis Pilaris: This is a harmless condition that causes small, rough patches on the skin, which can be itchy and worsen with heat.

Do Not Miss Diagnoses

  • Lymphoma: Although rare, lymphoma can cause itching, especially if it involves the lymph nodes in the armpits.
  • Hodgkin's Disease: This is a type of lymphoma that can cause itching, fever, and weight loss.
  • Thyroid Disorders: Certain thyroid conditions, such as hyperthyroidism, can cause itching and skin changes.

Rare Diagnoses

  • Darier's Disease: This is a rare genetic disorder that causes skin lesions and itching, especially in the armpits and groin area.
  • Hailey-Hailey Disease: This is a rare genetic disorder that causes blistering and itching in the skin folds, including the armpits.
  • Grover's Disease: This is a rare skin condition that causes itching, redness, and small bumps on the skin, especially in the armpits and groin area.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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