What is the cause of severe pruritus (itching) in the axillary (armpit) area bilaterally, exacerbated by hot weather, with small papules (bumps) on the anterior cervical (neck) region?

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Differential Diagnosis for Severe Itching in Armpit Area and Anterior Part of the Neck

Single Most Likely Diagnosis

  • Eczema (Atopic Dermatitis): This condition is characterized by itchy, inflamed skin and is often exacerbated by heat. The presence of small bumps and severe itching in the armpit area and anterior part of the neck, especially with increased symptoms in hot weather, aligns with eczema.

Other Likely Diagnoses

  • Contact Dermatitis: An allergic reaction or irritation from substances like deodorants, soaps, or clothing can cause itchy bumps in the armpits and neck.
  • Folliculitis: Inflammation of the hair follicles can lead to itchy, bumpy skin, particularly in areas like the armpits and neck where hair is more dense.
  • Heat Rash (Miliaria): Although more common in warmer, more humid environments, heat rash can cause small, itchy bumps and is worsened by hot weather.
  • Keratosis Pilaris: A condition characterized by rough, itchy patches on the skin, often appearing as small bumps, which can be exacerbated by dry skin and heat.

Do Not Miss Diagnoses

  • Lymphoma: Although rare, certain types of lymphoma can present with itchy skin lesions. It's crucial to rule out such serious conditions, especially if other systemic symptoms are present.
  • Hodgkin Lymphoma: Itching (pruritus) can be an early symptom of Hodgkin lymphoma, making it essential to consider in the differential diagnosis of unexplained, severe itching.

Rare Diagnoses

  • Grover's Disease: A rare skin condition characterized by itchy, bumpy lesions, often appearing on the trunk but can spread to other areas.
  • Darier's Disease: An inherited disorder that affects the skin, causing itchy, greasy bumps, which can appear in various parts of the body, including the armpits and neck.
  • Pityriasis Rubra Pilaris: A rare skin disorder that causes constant itching, scaling, and thickening of the skin, which can include the development of small bumps.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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