What is the most likely diagnosis for a 32-year-old woman presenting with progressive symmetric sensory loss ascending to the umbilicus, urinary urgency, frequency, nocturia, and a tight band-like sensation around her midabdominal region, with examination findings of slowed eye adduction, diffuse hyperreflexia, and decreased sensation to pinprick to the level of the umbilicus?

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Differential Diagnosis

  • Single most likely diagnosis
    • E) Transverse myelitis: This condition is characterized by inflammation across a segment of the spinal cord, which can cause progressive sensory loss, urinary symptoms, and a band-like sensation around the abdomen. The patient's symptoms, including ascending sensory loss to the umbilicus, urinary urgency and frequency, and a tight band-like sensation, are consistent with this diagnosis. The examination findings of slowed eye adduction and diffuse hyperreflexia also support this diagnosis.
  • Other Likely diagnoses
    • D) Spinal cord compression: This condition can cause similar symptoms to transverse myelitis, including progressive sensory loss and urinary symptoms. However, spinal cord compression is typically caused by a mass or lesion compressing the spinal cord, which may not be present in this patient.
    • B) Polyradiculopathy: This condition involves inflammation of multiple nerve roots, which can cause sensory loss and urinary symptoms. However, polyradiculopathy typically presents with more widespread and asymmetric symptoms.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • D) Spinal cord compression: Although this diagnosis may not be as likely as transverse myelitis, it is crucial to consider and rule out spinal cord compression, as it can be a medical emergency requiring prompt intervention.
    • A) Anterior cerebral artery occlusion: Although this diagnosis is unlikely, given the patient's symptoms and examination findings, it is essential to consider and rule out any potential vascular causes, as they can be life-threatening.
  • Rare diagnoses
    • C) Sensorimotor peripheral neuropathy: This condition involves damage to the peripheral nerves, which can cause sensory loss and other symptoms. However, the patient's symptoms and examination findings are not typical of a peripheral neuropathy, making this diagnosis less likely.
    • Other rare conditions, such as multiple sclerosis or neuromyelitis optica, could also be considered, but they are less likely given the patient's presentation and lack of other symptoms.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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