Can premenstrual dysmenorrhea (Premenstrual Cramps) cause hematuria (presence of blood in urine) and proteinuria (excess protein in urine), left lower quadrant (LLQ) abdominal pain with guarding (muscle tension) and an appearance of being ill?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 23, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Premenstrual Cramps with Hematuria, Proteinuria, LLQ Abdominal Pain, and Appearance of Being Ill

  • Single Most Likely Diagnosis
    • Ovarian Cyst or Torsion: This condition can cause lower left quadrant (LLQ) abdominal pain, and if the cyst ruptures, it may lead to hematuria and proteinuria due to the irritation of the surrounding tissues and potential involvement of the urinary tract. The appearance of being ill could be due to the severe pain and potential infection.
  • Other Likely Diagnoses
    • Urinary Tract Infection (UTI) or Pyelonephritis: These conditions can cause LLQ abdominal pain, hematuria, and proteinuria. The appearance of being ill could be due to the systemic infection.
    • Kidney Stone: A stone in the left ureter could cause LLQ abdominal pain, hematuria, and proteinuria. The severe pain could lead to an appearance of being ill.
    • Diverticulitis: Inflammation of the diverticula in the colon can cause LLQ abdominal pain, and if the diverticula rupture, it may lead to hematuria and proteinuria due to the involvement of the surrounding tissues.
  • Do Not Miss Diagnoses
    • Ectopic Pregnancy: Although less likely if the patient is experiencing premenstrual cramps, an ectopic pregnancy can cause LLQ abdominal pain, hematuria, and proteinuria. This condition is life-threatening and requires immediate attention.
    • Appendicitis: Although the pain is typically in the right lower quadrant, appendicitis can occasionally present with LLQ pain. This condition can lead to severe complications if not treated promptly.
    • Sepsis: Any infection, including UTI or diverticulitis, can lead to sepsis, a life-threatening condition that requires immediate attention.
  • Rare Diagnoses
    • Endometriosis: Although endometriosis can cause cyclic abdominal pain, it is less likely to cause hematuria and proteinuria. However, in rare cases, endometriosis can involve the urinary tract and cause these symptoms.
    • Vasculitis: Certain types of vasculitis, such as IgA nephropathy, can cause hematuria and proteinuria. However, these conditions are rare and would typically require additional symptoms and laboratory findings for diagnosis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.