What is the dose amount of Kenalog (Triamcinolone) injection for interstitial cystitis?

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From the FDA Drug Label

DOSAGE AND ADMINISTRATION General NOTE: CONTAINS BENZYL ALCOHOL (see PRECAUTIONS). IT SHOULD BE EMPHASIZED THAT DOSAGE REQUIREMENTS ARE VARIABLE AND MUST BE INDIVIDUALIZED ON THE BASIS OF THE DISEASE UNDER TREATMENT AND THE RESPONSE OF THE PATIENT

The FDA drug label does not answer the question.

From the Research

Kenalog (triamcinolone acetonide) injections for interstitial cystitis typically range from 10 to 40 mg per treatment, with the most common dose being 40 mg diluted in 10-20 mL of sterile saline or lidocaine solution, as part of a comprehensive treatment approach to reduce inflammation and alleviate symptoms 1.

Key Considerations

  • The medication is administered directly into the bladder wall via cystoscopy, targeting areas of inflammation and Hunner's lesions if present.
  • Treatment intervals generally range from 3 to 6 months depending on symptom relief duration, though some patients may require more frequent administration initially.
  • This steroid injection works by reducing inflammation in the bladder tissue, which helps decrease pain, urgency, and frequency associated with interstitial cystitis.

Potential Side Effects and Considerations

  • Patients should be aware that potential side effects include temporary worsening of symptoms for 24-48 hours after injection, urinary tract infection risk, and systemic steroid effects if absorbed.
  • The procedure is usually performed in an outpatient setting under local anesthesia or light sedation.

Comprehensive Treatment Approach

  • Kenalog injections are typically used as part of a comprehensive treatment approach that may include oral medications, dietary modifications, and other bladder therapies.
  • The diagnosis of Hunner-type interstitial cystitis or bladder pain syndrome requires cystoscopy to determine the presence or absence of Hunner lesions, and treatment should be tailored accordingly 1.

References

Research

Clinical guidelines for interstitial cystitis/bladder pain syndrome.

International journal of urology : official journal of the Japanese Urological Association, 2020

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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