Differential Diagnoses for Each Case
Case 1: Child with Sore Throat, Jaundice, and Hepatosplenomegaly
- Single Most Likely Diagnosis: Infectious Mononucleosis (EBV) - justified by the combination of sore throat, jaundice, hepatosplenomegaly, and fatigue.
- Other Likely Diagnoses:
- Viral Hepatitis - could explain jaundice and hepatosplenomegaly.
- Toxoplasmosis - might cause similar symptoms in immunocompromised patients.
- Do Not Miss Diagnoses:
- Leukemia or Lymphoma - although less likely, these conditions can present with hepatosplenomegaly and fatigue, and missing them could be fatal.
- Rare Diagnoses:
- Autoimmune Hemolytic Anemia - could explain jaundice but is less common in this context.
Case 2: Borderline Personality Disorder
- Single Most Likely Diagnosis: Borderline Personality Disorder - based on the video presentation, assuming it showed characteristic behaviors such as emotional instability, impulsivity, and intense interpersonal relationships.
- Other Likely Diagnoses:
- Histrionic Personality Disorder - might present with similar emotional dysregulation.
- Post-Traumatic Stress Disorder (PTSD) - could be a comorbid condition or mimic some symptoms.
- Do Not Miss Diagnoses:
- Bipolar Disorder - important to differentiate due to treatment implications.
- Rare Diagnoses:
- Factitious Disorder - less common but could present with dramatic, attention-seeking behavior.
Case 3: Patient with GCS 10
- Single Most Likely Diagnosis: Traumatic Brain Injury (TBI) - given the low GCS score, indicating severe impairment of consciousness.
- Other Likely Diagnoses:
- Stroke or Cerebral Vasculitis - could also lead to decreased consciousness.
- Do Not Miss Diagnoses:
- Status Epilepticus - requires immediate intervention.
- Meningitis or Encephalitis - infectious causes that could lead to severe neurological impairment.
- Rare Diagnoses:
- Brain Tumor - less likely but could cause increased intracranial pressure leading to decreased GCS.
Case 4: Erectile Dysfunction
- Single Most Likely Diagnosis: Psychogenic Erectile Dysfunction - given the context of work stress and relationship issues.
- Other Likely Diagnoses:
- Vasculogenic Erectile Dysfunction - related to atherosclerosis, especially in smokers.
- Neurogenic Erectile Dysfunction - could be due to diabetes, MS, or other neurological conditions.
- Do Not Miss Diagnoses:
- Hypogonadism - low testosterone levels could be a treatable cause.
- Rare Diagnoses:
- Peyronie's Disease - less common cause of erectile dysfunction due to penile deformity.
Case 5: Asthma Action Plan
- Not applicable as this case does not require a differential diagnosis.
Case 6: Patient on Lithium for BMD
- Single Most Likely Diagnosis: Bipolar Disorder (BMD) - given the patient is already on lithium.
- Other Likely Diagnoses:
- Schizoaffective Disorder - might also be treated with lithium.
- Do Not Miss Diagnoses:
- Lithium Toxicity - especially if there are signs of confusion, ataxia, or seizures.
- Rare Diagnoses:
- Other conditions treated with lithium, such as major depressive disorder with psychotic features.
Case 7: 9-Month-Old Child with Weight Concern
- Single Most Likely Diagnosis: Failure to Thrive (FTT) - due to inadequate weight gain.
- Other Likely Diagnoses:
- Gastroesophageal Reflux Disease (GERD) - could lead to feeding difficulties.
- Lactose Intolerance or Cow’s Milk Protein Allergy - might cause gastrointestinal symptoms leading to poor feeding.
- Do Not Miss Diagnoses:
- Congenital Heart Disease - could lead to failure to thrive due to increased metabolic demand.
- Inborn Errors of Metabolism - require early diagnosis for intervention.
- Rare Diagnoses:
- Endocrine Disorders (e.g., hypothyroidism) - less common causes of failure to thrive.
Case 8: Daughter with BMD
- Single Most Likely Diagnosis: Bipolar Disorder (BMD) - given the context.
- Other Likely Diagnoses:
- Borderline Personality Disorder - might present with mood instability.
- Do Not Miss Diagnoses:
- Schizophrenia - important to differentiate due to treatment implications.
- Rare Diagnoses:
- Other psychotic disorders - less common but could present with similar symptoms.
Case 9: 36 Weeks Pregnant with Itchy Rash
- Single Most Likely Diagnosis: Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP) - given the description and gestational age.
- Other Likely Diagnoses:
- Intrahepatic Cholestasis of Pregnancy (ICP) - could cause intense itching.
- Do Not Miss Diagnoses:
- Pemphigoid Gestationis - an autoimmune blistering disease.
- Rare Diagnoses:
- Polymorphic Eruption of Pregnancy (PEP) - less common than PUPPP.
Case 10: Young Male with Leg Pain on Walking
- Single Most Likely Diagnosis: Intermittent Claudication - due to smoking and exertional leg pain.
- Other Likely Diagnoses:
- Musculoskeletal Pain - could be due to overuse or strain.
- Do Not Miss Diagnoses:
- Deep Vein Thrombosis (DVT) - requires immediate intervention.
- Peripheral Artery Aneurysm - although less common, could cause claudication.
- Rare Diagnoses:
- Popliteal Artery Entrapment Syndrome - a less common cause of claudication.
Case 11: Young Male with Submandibular Lymph Node Pain
- Single Most Likely Diagnosis: Infectious Mononucleosis (EBV) - given the lymph node pain and potential for sore throat.
- Other Likely Diagnoses:
- Bacterial Pharyngitis - could cause lymphadenopathy.
- Do Not Miss Diagnoses:
- Tuberculosis (TB) - important to consider, especially with persistent lymphadenopathy.
- Lymphoma - although less likely, could present with lymph node pain.
- Rare Diagnoses:
- Cat-Scratch Disease - less common cause of lymphadenopathy.
Case 12: Young Lady with Past Chlamydia Infection
- Single Most Likely Diagnosis: Past Chlamydia Infection - given the history.
- Other Likely Diagnoses:
- Other Sexually Transmitted Infections (STIs) - could be present concurrently.
- Do Not Miss Diagnoses:
- Pelvic Inflammatory Disease (PID) - a complication of untreated STIs.
- Rare Diagnoses:
- Lymphogranuloma Venereum (LGV) - less common STI that could cause similar symptoms.
Case 13: 82-Year-Old Lady with Hip Surgery and Osteoporosis
- Single Most Likely Diagnosis: Osteoporotic Fracture - given the history of wedge fractures and osteoporosis.
- Other Likely Diagnoses:
- Osteopenia - a precursor to osteoporosis.
- Do Not Miss Diagnoses:
- Pathological Fracture - due to an underlying condition like cancer.
- Rare Diagnoses:
- Osteogenesis Imperfecta - a genetic disorder leading to brittle bones, less common in this age group.
Case 14: Eye Examination
- Not applicable as this case does not provide enough information for a differential diagnosis.
Case 15: Old Lady with Fracture of Head of Femur and Cognitive Impairment
- Single Most Likely Diagnosis: Postoperative Cognitive Dysfunction - given the recent surgery.
- Other Likely Diagnoses:
- Dementia - could be exacerbated by the surgery.
- Do Not Miss Diagnoses:
- Delirium - requires immediate intervention.
- Stroke or Transient Ischemic Attack (TIA) - could cause cognitive impairment post-surgery.
- Rare Diagnoses:
- Normal Pressure Hydrocephalus (NPH) - less common cause of cognitive impairment and gait disturbance.
Case 16: Middle-Aged Lady with Dizziness and Palpitations
- Single Most Likely Diagnosis: Cardiac Arrhythmia - given the symptoms of dizziness and palpitations.
- Other Likely Diagnoses:
- Hypertension - could cause similar symptoms.
- Do Not Miss Diagnoses:
- Myocardial Infarction (MI) - requires immediate intervention.
- Pulmonary Embolism (PE) - could cause dizziness and palpitations.
- Rare Diagnoses:
- Cardiac Tamponade - less common but life-threatening condition.