What is the overview of illness anxiety disorder (IAD), its diagnosis, and management?

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Last updated: February 7, 2025 • View editorial policy

From the Guidelines

Illness Anxiety Disorder (IAD) is a condition characterized by excessive worry about having a serious illness, despite medical reassurance and minimal or no somatic symptoms.

Diagnosis of IAD

  • Diagnosis is based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria, which include excessive worry about having a serious illness, excessive health-related behaviors, and significant distress or impairment in social, occupational, or other areas of life 1.
  • A thorough medical evaluation is necessary to rule out underlying medical conditions that may be contributing to the anxiety.
  • Screening tools, such as the Generalized Anxiety Disorder 7-item scale (GAD-7), can be used to identify individuals with anxiety disorders, including IAD 2.

Management of IAD

  • Cognitive-behavioral therapy (CBT) is a highly effective treatment for IAD, which helps individuals identify and challenge negative thought patterns and behaviors contributing to their anxiety 3.
  • Other forms of psychotherapy, such as acceptance and commitment therapy (ACT), may also be effective in reducing symptoms of IAD.
  • Medications, such as selective serotonin reuptake inhibitors (SSRIs), may be used as an adjunct to therapy in some cases, but are not typically the first line of treatment 4.

Key Considerations

  • Early identification and treatment of IAD are crucial to prevent the development of more severe anxiety symptoms and to improve quality of life 5.
  • A collaborative approach between healthcare providers, including primary care physicians and mental health specialists, is essential for effective management of IAD.
  • Patient education and support are critical components of treatment, as individuals with IAD often require reassurance and guidance to manage their anxiety and improve their overall well-being.

From the Research

Overview of Illness Anxiety Disorder (IAD)

  • Illness anxiety disorder (IAD) is characterized by preoccupation with fear of serious illness despite medical reassurance 6, 7, 8, 9
  • IAD is common, debilitating, challenging to treat, and results in high healthcare utilization 6, 9
  • Patients with IAD experience persistent anxiety or fear of having or acquiring a serious illness, which adversely affects their daily life 8, 9

Diagnosis of IAD

  • IAD is defined in the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-V) as the preoccupation with having or acquiring a serious illness, in the absence of somatic symptoms (or, if present, symptoms that are only mild in severity) 8
  • Clinically significant health anxiety is common, with estimates ranging up to 13% in the general adult population 9

Management of IAD

  • Evidence-based treatments, including psychopharmacology and cognitive behavioral therapy, can significantly alleviate symptoms 9
  • A therapeutic alliance with patients with IAD is essential, rather than ordering expensive or unnecessary diagnostic tests or treatment 8, 10
  • Collaboration between medical providers is essential to avoid the pitfalls of excess testing and medical treatment 9
  • Cognitive behavioral therapy (CBT) can be an effective treatment for IAD, and can be integrated into medical care and decision-making 6, 10
  • Minimizing medical work-up, reassurance, and reactive medication changes can help to simplify treatment and manage co-morbid conditions 6

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.