What is the intravenous (IV) dosage of Robaxin (Methocarbamol)?

From the Guidelines

Robaxin IV dosage should be 0.15–0.25 mg/kg per dose infused over 10 min in D5W, with a maximum initial dose of 1 mg, and may be repeated once if necessary. This dosage recommendation is based on the study published in Pediatrics in 2008 1. The study provides guidance on preparing for pediatric emergencies and suggests this specific dosage for IV administration of Robaxin. When administering Robaxin IV, it is essential to consider the following key points:

• The dose should be infused over 10 minutes to minimize the risk of adverse effects.
• The maximum initial dose is 1 mg, and repeating the dose should be done with caution.
• The solution should be prepared in D5W, which is a compatible IV solution.
• Monitoring of vital signs is crucial during infusion, especially in patients with pre-existing medical conditions. According to the study 1, this dosage regimen is appropriate for pediatric patients, and it is crucial to follow these guidelines to ensure safe and effective treatment.

From the FDA Drug Label

DOSAGE AND ADMINISTRATION For Intravenous and Intramuscular Use Only. Total adult dosage should not exceed 30 mL (3 vials) a day for more than 3 consecutive days except in the treatment of tetanus. For the relief of symptoms of moderate degree, one dose of 1 gram (one 10 mL vial) may be adequate. For the severest cases or in postoperative conditions in which oral administration is not feasible, additional doses of 1 gram may be repeated every 8 hours up to a maximum of 3 g/day for no more than 3 consecutive days. Directions for Intravenous Use ROBAXIN Injectable may be administered undiluted directly into the vein at a maximum rate of three mL per minute

The recommended IV dosage of Robaxin is:

• 1 gram (10 mL) for moderate symptoms
• Up to 3 grams per day in divided doses every 8 hours for severe cases, not to exceed 3 consecutive days 2 Key points:
• Maximum daily dose: 30 mL (3 vials) for no more than 3 consecutive days
• Maximum infusion rate: 3 mL per minute
• Maximum single dose for IV infusion: 1 vial (10 mL) in 250 mL of IV fluid

From the Research

Robaxin IV Dosage

• The provided studies do not specifically mention the IV dosage of Robaxin (methocarbamol) 3, 4, 5, 6, 7.
• However, it is known that Robaxin is a muscle relaxant used to treat muscle spasms and pain 4.
• The studies discuss the use of various muscle relaxants, including oral medications and intrathecal administration, but do not provide information on IV dosage specifically 3, 4, 5, 7.
• One study mentions that muscle relaxants may be useful for acute low back pain, but does not specify the dosage or route of administration 6.
• Another study discusses the pharmacological management of post-stroke muscle spasticity, but does not provide information on Robaxin IV dosage 7.

Available Information on Muscle Relaxants

• The studies provide information on the efficacy and safety of various muscle relaxants, including benzodiazepines, non-benzodiazepines, and antispasticity drugs 3, 4, 5, 7.
• They discuss the use of these medications for conditions such as rheumatoid arthritis, musculoskeletal pain, and spasticity 3, 4, 5, 7.
• However, the specific information on Robaxin IV dosage is not available in the provided studies 3, 4, 5, 6, 7.