What is the cause of a 64-year-old male's acute left knee pain and swelling without a history of trauma?

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Differential Diagnosis for Left Knee Pain and Swelling

Single Most Likely Diagnosis

  • Osteoarthritis (OA) flare-up: The patient's age, history of arthritis, and recent activity (walking on the sand) could have triggered an OA flare-up, leading to knee pain and swelling. The improvement with Tylenol arthritis and ice also supports this diagnosis.

Other Likely Diagnoses

  • Meniscal tear or ligament sprain: The patient's history of frequently hitting his legs on objects and the acute onset of pain and swelling suggest a possible meniscal tear or ligament sprain.
  • Bursitis: The patient's occupation and activities could have led to bursitis, which is an inflammation of the fluid-filled sacs that cushion the joints.
  • Tendinitis: The patient's age and activity level could have contributed to tendinitis, which is an inflammation of the tendons.

Do Not Miss Diagnoses

  • Deep vein thrombosis (DVT): Although the patient denies calf pain and has a negative Homan's sign, DVT is a potentially life-threatening condition that should not be missed. The patient's recent activity and swelling could be masking symptoms of DVT.
  • Septic arthritis: The patient's age and recent activity could have led to a bacterial infection in the joint, which is a medical emergency.
  • Fracture: Although the patient does not remember a specific injury, a fracture could have occurred, and it is essential to rule out this possibility.

Rare Diagnoses

  • Gout or pseudogout: The patient's age and acute onset of pain and swelling could suggest a crystal arthropathy, such as gout or pseudogout.
  • Hemarthrosis: The patient's history of frequent trauma to the legs could have led to bleeding into the joint, which is a rare but possible diagnosis.
  • Neoplastic or inflammatory conditions: Conditions such as rheumatoid arthritis, lupus, or bone tumors could be causing the patient's symptoms, although these are less likely given the patient's presentation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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