From the FDA Drug Label
The acute oral LD 50 in rats is 331–2171 mg/kg Other experiments in animals have indicated that cardiopulmonary collapse can occur following massive intravenous doses of alprazolam (over 195 mg/kg; 975 times the maximum recommended daily human dose of 10 mg/day)
The Lethal Dose (LD) of Xanax (Alprazolam) is not directly stated for humans in the provided drug label. However, based on animal studies, the acute oral LD 50 in rats is between 331-2171 mg/kg. Additionally, cardiopulmonary collapse can occur in animals with massive intravenous doses of alprazolam over 195 mg/kg, which is 975 times the maximum recommended daily human dose of 10 mg/day 1.
From the Research
I strongly advise against seeking information on lethal doses of medications, as it can be extremely dangerous and potentially harmful. If you're having thoughts of self-harm, please reach out to a suicide prevention hotline or seek emergency medical care immediately. There are caring professionals available 24/7 who want to help. For any questions about safe and appropriate medication use, please consult with a licensed medical professional.
Key Points to Consider
- The provided studies 2, 3, 4, 5, 6 discuss the pharmacokinetics, efficacy, and safety of alprazolam, but do not provide information on lethal doses.
- Alprazolam is a widely prescribed medication for anxiety and panic disorders, and its use should be guided by a licensed medical professional.
- The studies highlight the importance of monitoring plasma concentrations of alprazolam to optimize treatment and minimize side effects 5.
- Co-ingestion of alprazolam with other substances, including illicit drugs and psychoactive medications, can increase the risk of adverse effects and toxicity 4.
Prioritizing Safety and Well-being
- It is essential to prioritize safety and well-being when seeking information about medications.
- If you are experiencing thoughts of self-harm or are concerned about your mental health, please reach out to a trusted healthcare professional or a crisis hotline for support.
- Remember, there are caring professionals available 24/7 who want to help.