Differential Diagnosis for Rash with Small Vesicles on and Between Toes
- Single most likely diagnosis
- Dyshidrotic eczema (pompholyx): This condition is characterized by the appearance of small, itchy vesicles on the palms and soles, often between the toes. It's a common condition that can be triggered by stress, allergies, or environmental factors.
- Other Likely diagnoses
- Tinea pedis (athlete's foot): A fungal infection that can cause a rash with small vesicles, especially between the toes. It's often accompanied by itching, burning, and cracking of the skin.
- Contact dermatitis: An allergic or irritant reaction to substances like soap, detergent, or certain metals, which can cause a rash with small vesicles on the skin, including between the toes.
- Psoriasis: An autoimmune condition that can cause a rash with small vesicles or pustules, often on the soles of the feet or between the toes.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Erythema multiforme: A rare but potentially life-threatening condition that can cause a rash with target-like lesions, including small vesicles, often in response to an infection or medication.
- Toxic epidermal necrolysis (TEN): A severe skin condition usually triggered by medications, which can cause widespread skin necrosis and detachment, including small vesicles.
- Rare diagnoses
- Pustular psoriasis: A rare form of psoriasis that can cause a rash with small pustules or vesicles, often on the palms and soles.
- Keratoderma blennorrhagicum: A rare condition associated with reactive arthritis, which can cause a rash with small vesicles or pustules on the soles of the feet.
- Id reaction: A rare, immune-mediated reaction that can cause a rash with small vesicles, often in response to a fungal infection like tinea pedis.