What is the recommended dosage of ibuprofen (Nonsteroidal Anti-Inflammatory Drug (NSAID)) for a 14-year-old female for pain relief?

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Last updated: May 24, 2025View editorial policy

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From the Guidelines

For a 14-year-old female experiencing pain, the recommended dose of ibuprofen is 400 mg every 6 hours as needed, not exceeding 1,200 mg in 24 hours, as per the most recent guideline from the American College of Physicians 1.

Key Considerations

  • The dose of ibuprofen should be individualized based on the patient's weight and response to treatment.
  • Ibuprofen should be taken with food or milk to reduce stomach irritation.
  • The medication typically begins working within 30-60 minutes and lasts about 4-6 hours.
  • If pain persists beyond 3 days or fever beyond 3 days, consult a healthcare provider.
  • Ibuprofen works by reducing inflammation and blocking pain signals by inhibiting prostaglandin production.

Important Safety Information

  • Side effects may include stomach upset, so discontinue use and seek medical attention if stomach pain, nausea, or other concerning symptoms develop.
  • Patients should be aware of medication overuse and potential interactions with other medications.
  • The American College of Physicians recommends considering alternative treatments, such as triptans or acetaminophen, if ibuprofen is not effective or tolerated 1.

Dosing Guidelines

  • Start with the recommended dose of 400 mg every 6 hours as needed.
  • Do not exceed 1,200 mg in 24 hours.
  • Adjust the dose based on the patient's response to treatment and weight.
  • Consider consulting a healthcare provider if the patient has a history of stomach problems or is taking other medications that may interact with ibuprofen 1.

From the Research

Dosage of Ibuprofen for a 14-Year-Old Female

The recommended dosage of ibuprofen for adolescents is not explicitly stated in the provided studies. However, we can look at the general guidelines for ibuprofen dosage:

  • The study 2 mentions that low doses of ibuprofen (800-1,200 mg day(-1)) are approved for non-prescription (over-the-counter) sale and have a good safety profile.
  • The study 3 uses a dose of 800 mg of ibuprofen for adult patients with acute musculoskeletal pain.

Considerations for Pediatric Patients

When it comes to pediatric patients, the dosage of ibuprofen is typically lower than for adults. The study 2 mentions that pediatric use of ibuprofen is reviewed, and the main results are that the drug is relatively safe and effective as a treatment of acute pain and fever.

Possible Dosage Range

Based on the available information, a possible dosage range for a 14-year-old female could be:

  • 400-600 mg every 6-8 hours as needed for pain relief, not to exceed 1200 mg in 24 hours. However, it is essential to consult a healthcare professional to determine the appropriate dosage and treatment plan for a specific individual.

Important Notes

  • Ibuprofen should be used with caution in pediatric patients, and the dosage should be adjusted according to the patient's weight and medical condition.
  • The study 4 suggests that ibuprofen is usually superior to paracetamol in producing more patients with the degree of pain relief that patients feel worthwhile.
  • The study 5 shows that ibuprofen can elevate blood pressure in women with severe pre-eclampsia, but this may not be directly relevant to a 14-year-old female patient.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Ibuprofen: pharmacology, efficacy and safety.

Inflammopharmacology, 2009

Research

Ibuprofen versus acetaminophen as a post-partum analgesic for women with severe pre-eclampsia: randomized clinical study.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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