What are the differential diagnoses of chest pain (thoracic pain)?

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Differential Diagnosis of Chest Pain

The differential diagnosis of chest pain is broad and can be categorized into several groups. Here's a breakdown of the possible causes:

  • Single Most Likely Diagnosis
    • Gastroesophageal Reflux Disease (GERD): This is often the most common cause of chest pain, especially if the pain is related to eating or worsens with lying down. GERD can cause a burning sensation in the chest that may be mistaken for cardiac pain.
  • Other Likely Diagnoses
    • Musculoskeletal Pain: Strained muscles or costochondritis (inflammation of the cartilage that connects the ribs to the breastbone) can cause chest pain, especially if the pain is sharp and worsens with movement.
    • Asthma or Chronic Obstructive Pulmonary Disease (COPD): Respiratory conditions can cause chest pain or tightness, especially if the patient is experiencing an exacerbation.
    • Pneumonia or Pulmonary Embolism: Although less common, these conditions can cause chest pain, especially if the patient has a history of respiratory issues or recent travel.
  • Do Not Miss Diagnoses
    • Myocardial Infarction (MI): Although not the most common cause of chest pain, MI is a life-threatening condition that requires immediate attention. The classic presentation is a squeezing or pressure-like pain in the center of the chest that radiates to the arm, neck, or jaw.
    • Aortic Dissection: A tear in the aorta can cause severe, tearing chest pain that radiates to the back. This condition is rare but deadly if missed.
    • Pulmonary Embolism: A blood clot in the lungs can cause sudden, severe chest pain and shortness of breath. This condition requires immediate attention.
  • Rare Diagnoses
    • Pericarditis: Inflammation of the sac surrounding the heart can cause sharp, stabbing chest pain that worsens with movement.
    • Esophageal Spasm: Abnormal muscle contractions in the esophagus can cause chest pain that mimics cardiac pain.
    • Pneumothorax: A collapsed lung can cause sudden, severe chest pain and shortness of breath, especially if the patient has a history of lung disease.

It's essential to note that the diagnosis of chest pain requires a thorough medical history, physical examination, and diagnostic tests to determine the underlying cause.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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