Can scarlet fever cause desquamation of palmar skin?

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Last updated: May 24, 2025View editorial policy

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From the Guidelines

Scarlet fever is not directly associated with causing palmar skin to slough off, however, a similar condition, Kawasaki disease, can cause desquamation of the fingers and toes that may extend to involve the palms and soles. The evidence from the American Heart Association 1 suggests that desquamation in Kawasaki disease usually begins in the periungual region within 2 to 3 weeks after the onset of fever. Key characteristics of this condition include:

  • Erythema of the palms and soles
  • Firm and sometimes painful induration of the hands or feet
  • Desquamation of the fingers and toes that may extend to the palms and soles
  • Deep transverse grooves across the nails (Beau’s lines) at 1 to 2 months after fever onset. It's essential to note that scarlet fever, caused by group A Streptococcus bacteria, has distinct clinical features, including a rash and fever, but the provided evidence does not directly link it to palmar skin sloughing off. If skin peeling on the palms is observed, especially following a fever and rash, it's crucial to seek medical attention for proper diagnosis and treatment, as various conditions could be responsible for this symptom.

From the Research

Scarlet Fever Symptoms

  • The studies 2, 3, 4, 5, 6 describe the typical symptoms of scarlet fever, including a distinctive rash, sore throat, and flushed cheeks.
  • The rash is a key diagnostic feature, reported in 89% of cases in one study 5.
  • Other symptoms, such as fever, enlarged lymph nodes, and tonsillar exudate, are also common 6.

Skin Sloughing

  • None of the studies 2, 3, 4, 5, 6 specifically mention palmar skin sloughing as a symptom of scarlet fever.
  • The studies focus on the typical symptoms of scarlet fever, such as rash, sore throat, and fever, but do not discuss skin sloughing in detail.

Complications

  • One study 2 mentions that untreated scarlet fever can lead to complications, but does not specify what these complications are.
  • Another study 4 recommends treating scarlet fever with antibiotics to reduce the risk of complications, but does not provide further information on what these complications might be.
  • There is no direct evidence in the studies to suggest that scarlet fever can cause palmar skin to slough off.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Scarlet fever: a guide for general practitioners.

London journal of primary care, 2017

Research

Scarlet fever.

Nursing standard (Royal College of Nursing (Great Britain) : 1987), 2016

Research

Managing scarlet fever.

Drug and therapeutics bulletin, 2017

Research

Scarlet fever: A not so typical exanthematous pharyngotonsillitis (based on 171 cases).

Enfermedades infecciosas y microbiologia clinica, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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