What is the diagnosis for a 25-year-old woman with erythematous scaly lesions and a recent history of pharyngitis, with a throat culture positive for Streptococcus?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 21, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis

  • Single most likely diagnosis
    • Guttate Psoriasis: This condition is characterized by the sudden onset of small, red, scaly lesions, often triggered by a streptococcal infection, which fits the patient's history of recent sore throat and positive throat culture for Streptococcus. The drop-like appearance of the plaques is also typical for guttate psoriasis.
  • Other Likely diagnoses
    • Pityriasis Rosea: Although the trigger is often unknown, the presentation of small, red, scaly lesions, particularly with a herald patch, could be considered. However, the direct link to a streptococcal infection and the specific description of drop-like plaques makes this less likely.
    • Secondary Syphilis: This condition can present with a wide range of skin manifestations, including small, red, scaly lesions. However, it would typically be accompanied by other systemic symptoms and a history that might suggest exposure.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Meningococcemia: Although rare and not directly suggested by the skin lesions alone, any condition that presents with a sudden onset of a rash, especially in the context of a recent infection, should prompt consideration of meningococcemia due to its high mortality rate if not promptly treated.
    • Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: These are severe skin conditions usually triggered by medications or infections. While the presentation might not exactly match, any widespread skin condition with a potential for severe consequences should be considered, especially if there's a suspicion of a drug or infectious trigger.
  • Rare diagnoses
    • Kawasaki Disease: Typically seen in children, it could be considered in young adults with a rash and recent infection, though other criteria such as fever, lymphadenopathy, and desquamation in the hands and feet would need to be present.
    • Erythema Multiforme: This condition can present with target lesions and is often associated with infections (including streptococcal) or medications. While it's a possibility, the description provided leans more towards guttate psoriasis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.